Sökning: "Steroid receptors"

Visar resultat 6 - 10 av 92 avhandlingar innehållade orden Steroid receptors.

  1. 6. Sex steroid hormone receptors : inner ear and hearing

    Författare :Rusana Simonoska; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : It is well known that hearing loss is more profound in elderly males than females, regardless of noise exposure. Also, an age-related hearing decline starts much earlier in males, already after the age of 30, while in women, the decline does not start until the age of 50. LÄS MER

  3. 7. Functional importance of estrogen receptors in the periodontium

    Författare :Daniel Nebel; Malmö högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Estrogen; Estrogen receptors; LPS; Periodontium; PDL cells; Gingival epithelial cells;

    Sammanfattning : Östrogen är ett kvinnligt könshormon som även har andra effekter. Östrogen verkar i cellkärnan genom att binda till en östrogenreceptor (ER), som finns i två olika typer, ERα och ERβ. Parodontit (tandlossning) är en inflammationssjukdom som drabbar tandens fäste som svar på bakterier som normalt finns i munhålan. LÄS MER

  4. 8. Clinical Aspects of Hereditary Breast Cancer

    Författare :Niklas Loman; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; Cytologi; onkologi; cancerology; oncology; Cytology; Age of onset; Survival analysis; Incidence; Male breast cancer; Steroid receptors; BRCA2; BRCA1; Breast cancer; hereditary;

    Sammanfattning : A positive family history of breast cancer (BC) is one of the strongest predictors of the disease. Two major BC susceptibility genes, BRCA1 and BRCA2 were identified about a decade ago. In this thesis, studies of different biological. clinical and epidemiological aspects of hereditary BC are presented. LÄS MER

  5. 9. Male Subfertility and Prostate Cancer Risk: Epidemiological and Genetic Studies

    Författare :Yasir Ruhayel; Malmö Molekylärgenetisk reproduktionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytoplasmic and nuclear; Receptors; Prostatic neoplasms; genetic; Polymorphism; male; Infertility; Hypogonadism; Genetic association studies; Case–control studies; Androgens;

    Sammanfattning : Androgen action plays a pivotal role in male reproductive tract physiology and pathology. The androgen receptor (AR) gene harbors two codon repeat tracts: the CAG and GGN repeats, encoding corresponding amino acid sequences of variable length; the polyglutamine and polyglycine stretches, respectively. LÄS MER

  7. 10. The relative importance of sex steroid receptors for bone metabolism

    Författare :Sofia Movérare-Skrtic; Göteborgs universitet; []
    Nyckelord :bone; estrogen; androgen; transgenic; microarray;

    Sammanfattning : Estrogen deficiency increases the risk of a wide variety of pathological conditions including osteoporosis. Morbidity from osteoporosis is substantial in both men and women. LÄS MER