Sökning: "Case–control studies"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden Case–control studies.

  1. 1. Male Subfertility and Prostate Cancer Risk: Epidemiological and Genetic Studies

    Författare :Yasir Ruhayel; Malmö Molekylärgenetisk reproduktionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytoplasmic and nuclear; Receptors; Prostatic neoplasms; genetic; Polymorphism; male; Infertility; Hypogonadism; Genetic association studies; Case–control studies; Androgens;

    Sammanfattning : Androgen action plays a pivotal role in male reproductive tract physiology and pathology. The androgen receptor (AR) gene harbors two codon repeat tracts: the CAG and GGN repeats, encoding corresponding amino acid sequences of variable length; the polyglutamine and polyglycine stretches, respectively. LÄS MER

  3. 2. Genetic variation and prostate cancer : population-based association studies in Sweden

    Författare :Sara Lindström; Henrik Grönberg; Fredrik Wiklund; John Todd; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; epidemiology; SRD5A2; ERG; progression; genetics; association studies; polymorphism; haplotype; CDH1; AR; CYP17; Oncology; Onkologi;

    Sammanfattning : Prostate cancer constitutes the most common malignancy and the most common cause of cancer‐related death in Swedish men. A large body of evidence suggests that inherited genetic variants contribute to both development and progression of prostate cancer. LÄS MER

  4. 3. Cerebrospinal fluid studies of bipolar disorder

    Författare :Anniella Isgren; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bipolar disorder; Cerebrospinal fluid; Biomarkers; Pathophysiology; Proteomics; Neuroimmunology; Cytokines;

    Sammanfattning : The pathophysiology of bipolar disorder remains to be elucidated. One approach to studying brain processes is analysis of cerebrospinal fluid (CSF). LÄS MER

  5. 4. Studies on colonoscopy and inflammatory conditions of the colon

    Författare :Bjarki Alexandersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Colonoscopy is a key investigative tool in inflammatory bowel disease and diverticular disease, but elements of the pathogenesis, symptomatology and safety of procedures in these two conditions remain unknown. The best surveillance method for colorectal cancer in inflammatory bowel disease (IBD) is debated. LÄS MER

  7. 5. Molecular epidemiologic studies on helicobacter pylori infection and stomach cancer risk

    Författare :Zongli Zheng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Helicobacter pylori;

    Sammanfattning : Helicobacter pylori (H. pylori) infection increases stomach cancer risk. The aim of this thesis was to study genetic susceptibility from the host and to develop molecular methods for future characterization of bacterial virulence factors in longitudinal cohorts. LÄS MER