Sökning: "Solid-phase extraction"

Visar resultat 16 - 20 av 105 avhandlingar innehållade orden Solid-phase extraction.

  1. 16. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids

    Författare :Daniel Blessborn; Yngve Bergqvist; Anders Helander; Högskolan Dalarna; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Malaria; Chloroquine; Quinine; Sulfadoxine; Pyrimethamine; Mefloquine; Lumefantrine; Amodiaquine; Pyronaridine; Proguanil; Atovaquone; Sampling paper; Dried blood spots; Capillary blood; Antimalarial drugs; Solid-phase extraction; Liquid chromatography.; Chemistry;

    Sammanfattning : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. LÄS MER

  3. 17. Drug Analysis : Bioanalytical Method Development and Validation

    Författare :Mikaela Malm; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Nyckelord :Analytical chemistry; African trypanosomiasis; calibration model; chiral chromatography; dried blood spots; eflornithine; evaporative light-scattering detection; HIV AIDS; lamivudine; liquid chromatography; malaria; nevirapine; piperaquine; pneumonia; solid-phase extraction; sulfadoxine; sulfamethoxazole; validation; zidovudine; Analytisk kemi;

    Sammanfattning : This thesis describes bioanalytical methods for drug determination in biological matrixes, with drugs in focus used against diseases largely affecting low-income countries. Solid-phase extraction is used for sample cleanup, and processed samples are analyzed by liquid chromatography. LÄS MER

  4. 18. Poly (butylene succinate) and poly (butylene adipate) : quantitative determination of degradation products and application as PVC plasticizers

    Författare :Annika Lindström; Minna Hakkarainen; Ann-Christine Albertsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; solid phase extraction; degradation products; poly butylene succinate ; poly butylene adipate ; GC-MS; PVC; plasticizer; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : A solid phase extraction (SPE) method was developed for simultaneous extraction of dicarboxylic acids and diols formed during hydrolysis of poly(butylene succinate), PBS, and poly(butylene adipate), PBA. The developed SPE method and subsequent GC-MS analysis were used to extract, identify and quantify low molecular weight products migrating from linear and branched poly(butylene adipate) (PBA) and poly(butylene succinate) (PBS) during aging in aqueous media. LÄS MER

  5. 19. Development of Field-adapted Analytical Methods for the Determination of New Antimalarial Drugs in Biological Fluids

    Författare :Niklas Lindegårdh; Karin Markides; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; LC; liquid chromatography; biological samples; SPE; solid phase extraction; validation; antimalarial drugs; amodiaquine; piperaquine; atovaquone; dried blood spots; Analytisk kemi; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : This thesis deals with the development of analytical methods for the determination of new antimalarial drugs in biological fluids. The goal was to develop methods that facilitate clinical studies performed in the field, such as capillary blood sampling onto sampling paper. LÄS MER

  7. 20. Methodologies to assess the fate of polar organic compounds in aquatic environments

    Författare :Jörgen Magnér; Tomas Alsberg; Dag Broman; Jan-Åke Jönsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Passive equilibrium sampler; Absorbent; Polar organic compounds; Liquid chromatography-mass spectrometry; Partitioning coefficient; Fulvic acid; Sediment; PEVAC; Bag-SPE; Solid phase extraction; Pharmaceuticals; Wastewater; Sea water; UPLC-QToF; Environmental chemistry; Miljökemi; Analytical chemistry; Analytisk kemi; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Polar organic compounds (POCs) are chemicals with polar functional groups in their structure. The functional groups make the compounds hydrophilic and less prone to partition with biota. However, the knowledge of their fate is limited due to difficulties associated with their measurements. LÄS MER