Sökning: "Atovaquone"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet Atovaquone.

  1. 1. Drug repositioning in chemoprevention of colorectal cancer

    Författare :Naiqi Zhang; Allmänmedicin och klinisk epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug repositioning; Colorectal cancer CRC ; Pharmacoepidemiology; Chemoprevention; Melatonin; Proguanil; Atovaquone; Selective serotonin reuptake inhibitor SSRI ;

    Sammanfattning : BackgroundColorectal cancer (CRC) ranks as the third most frequently occurring cancer and the second leading cause of cancer-related deaths worldwide. In response to the high demand for an effective prevention strategy, chemoprevention, using medications to block the pathogenetic pathways of disease, might be an attractive strategy to offer a more effective option at a low cost. LÄS MER

  3. 2. Development of Field-adapted Analytical Methods for the Determination of New Antimalarial Drugs in Biological Fluids

    Författare :Niklas Lindegårdh; Karin Markides; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; LC; liquid chromatography; biological samples; SPE; solid phase extraction; validation; antimalarial drugs; amodiaquine; piperaquine; atovaquone; dried blood spots; Analytisk kemi; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : This thesis deals with the development of analytical methods for the determination of new antimalarial drugs in biological fluids. The goal was to develop methods that facilitate clinical studies performed in the field, such as capillary blood sampling onto sampling paper. LÄS MER

  4. 3. Development of field-adapted analytical methods for the determination of new antimalarial drugs in biological fluids

    Författare :Niklas Lindegårdh; Högskolan Dalarna; []
    Nyckelord :LC; liquid chromatography; biological samples; SPE; solid phase extraction; validation; antimalarial drugs; amodiaquine; piperaquine; atovaquone; dried blood spots;

    Sammanfattning : .... LÄS MER

  5. 4. Pharmacokinetics and dynamics of atovaquone and proguanil (Malarone®)

    Författare :Mita M Thapar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Malarone; Atovaquone; proguanil; cycloguanil; pharmacokinetics; drug interactions; pharmacodynamics; resistance;

    Sammanfattning : Malarone® is a fixed dose combination of atovaquone and proguanil and is mainly used for prophylaxis against P. falciparum malaria as an alternative to Lariamo® or chloroquine+proguanil. LÄS MER

  7. 5. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids

    Författare :Daniel Blessborn; Yngve Bergqvist; Anders Helander; Högskolan Dalarna; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Malaria; Chloroquine; Quinine; Sulfadoxine; Pyrimethamine; Mefloquine; Lumefantrine; Amodiaquine; Pyronaridine; Proguanil; Atovaquone; Sampling paper; Dried blood spots; Capillary blood; Antimalarial drugs; Solid-phase extraction; Liquid chromatography.; Chemistry;

    Sammanfattning : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. LÄS MER