Sökning: "Population study"

Visar resultat 21 - 25 av 5300 avhandlingar innehållade orden Population study.

  1. 21. Population Genetic Methods and Applications to Human Genomes

    Författare :Lucie Gattepaille; Mattias Jakobsson; Kevin Thornton; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Population genetics; Human evolution; Genetic diversity; Genetic differentiation; Adaptation; Population structure; Effective population size; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Population Genetics has led to countless numbers of fruitful studies of evolution, due to its abilities for prediction and description of the most important evolutionary processes such as mutation, genetic drift and selection. The field is still growing today, with new methods and models being developed to answer questions of evolutionary relevance and to lift the veil on the past of all life forms. LÄS MER

  3. 22. On the aetiology of ALS : a comprehensive genetic study

    Författare :Caroline Ingre; Peter M Andersen; Rayomand Press; Siddharthan Chandran; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; risk factor; VAPB; SOD1; amyotrophic lateral sclerosis; ATXN2; SMN1; SMN2; PFN1; 50 bp deletion in SOD1 promotor; population-specific genetic variations; Neurology; neurologi;

    Sammanfattning : Introduction: Amyotrophic lateral sclerosis (ALS) is a deadly, progressive neuromuscular disease that affects individuals all over the world. About 10% of the patients have a familial predisposition (FALS) while the remainder of cases are isolated or sporadic (SALS) and of unknown cause. LÄS MER

  4. 23. Finding fitness : empirical and theoretical explorations of inferring fitness effects from population-level SNP data

    Författare :Bea Angelica Andersson; Xiao-Ru Wang; Åke Brännström; Tanja Slotte; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; distribution of fitness effects; site frequency spectra; missing data filtering; downsampling; imputation; sample size; population structure; inbreeding; selfing; homozygosity; Arabidopsis; Pinus; DFE-alpha; SLiM; population genomics; adaptation; biology; biologi; evolutionär genetik; evolutionary genetics; populationsbiologi; Population Biology; molekylärbiologi; Molecular Biology; Genetics; genetik;

    Sammanfattning : The distribution of fitness effects (DFE) describes the likelihood that a new mutation has a specific effect on the fitness of an individual in a given population. The shape of the DFE is a result of several factors such as population size, mating system and selective environment, and can in turn influence the evolutionary potential of a species. LÄS MER

  5. 24. Changing population distribution in Sweden : long term trends and contemporary tendencies

    Författare :Johan Håkansson; Umeå universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Population distribution; redistribution; Sweden; geographical levels; concentration; dispersion; accessibility; migration; natural population change; age composition;

    Sammanfattning : The aim of the thesis is to describe and analyse the population redistribution in Sweden at different geographical levels from the beginning of the 19th century to the end of the 20th century. The analysis is approached in three different ways. First, the redistribution at different geographical levels is analysed (papers I and II). LÄS MER

  7. 25. Homocysteine and vascular morbidity and dementia in women. A prospective population study

    Författare :Dimitri Zylberstein; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Women; population study; dementia; Homocysteine; MTHFR; myocardial infarctions; lacunar infarcts; epidemiology;

    Sammanfattning : Homocysteine and cardiovascular morbidity and dementia in women - A prospective population study Dimitri Edin Zylberstein Institute of Medicine, The Sahlgrenska Academy, Department of Public Health and Community Medicine, Section of Primary Health Care, University of Gothenburg Abstract Purpose. The purpose of this thesis was to study cardiovascular morbidity and dementia in relation to homocysteine levels in women in a longitudinal, prospective population study over several decades. LÄS MER