Sökning: "Phagocytosis : immunology"

Visar resultat 1 - 5 av 36 avhandlingar innehållade orden Phagocytosis : immunology.

  1. 1. Mechanisms involved in macrophage phagocytosis of apoptotic cells

    Författare :Anna Nilsson; Per-Arne Oldenborg; Karl-Eric Magnusson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; macrophages; dendritic cells; phagocytosis; apoptotic cells; senescent erythrocytes; CD47; SIRPalpha; LRP1; calreticulin; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Efficient removal of apoptotic cells is critical for development, tissue remodelling, maintenance of homeostasis, and response to injury. Phagocytosis of apoptotic cells is mediated by many phagocytic receptors, soluble bridging molecules, and pro-phagocytic ligands on the surface of apoptotic cells. LÄS MER

  3. 2. Malarial anaemia : the potential involvement of Plasmodium falciparum rhoptry proteins

    Författare :Nancy Awah; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Malaria remains a challenging health problem in malaria endemic regions. Infection with malaria invariably leads to anaemia. The groups at risk of developing malarial anaemia include children below the age of five years and pregnant women, especially primigravidae. LÄS MER

  4. 3. Role of alveolar epithelial cells in macrophage responses against mycobacterial infections

    Författare :Olga Daniela Chuquimia Flores; Carmen Fernández; Diana Boraschi; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lung; alveolar epithelial cells; macrophages; AEC-derived media; control of intracellular bacterial growth; mycobacterial infections; immunologi; Immunology;

    Sammanfattning : This thesis aimed to investigate the role of alveolar epithelial cells (AEC) on immune responses against mycobacterial infections, specifically, the role of AEC in modulating macrophage functions through the secretion of broad variety of factors.In paper I, we compared murine AEC with interstitial macrophages (PuM) in their ability to take up and control mycobacterial growth and their capacity as antigen-presenting cells. LÄS MER

  5. 4. The mast cell transcriptome and the evolution of granule proteins and Fc receptors

    Författare :Srinivas Akula; Lars Hellman; Sandra Kleinau; Arne Egesten; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cell; Fc receptors; Granule serine protease; Evolution and transcriptome.; Immunologi; Immunology;

    Sammanfattning : Protection against disease-causing pathogens, known as immunity, involves numerous cells organs, tissues and their products. To able to understand the biology of immune cells (hematopoietic cells) and their role in an immune system, we have used several different methods, including transcriptome analyses, bioinformatics, production of recombinant proteins and analyses of some of them, focusing on the granule proteases by substrate phage display. LÄS MER

  7. 5. Life and death of human B cells in health and disease

    Författare :Andy Dernstedt; Mattias N. E. Forsell; Clas Ahlm; Jonas Klingström; Mats Bemark; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; b cells; antibody; hantavirus; germinal centre; phagocytosis; selection; DAF; vaccination; rituximab;

    Sammanfattning : B cells provide one of the key mechanisms of immunological memory, which is theproduction of neutralising antibodies. How B cells respond to infections and vaccinationgives clues to how the development of the immunological memory is facilitated, and canthus lead to a deeper understanding of why the immune system sometimesmalfunctions. LÄS MER