Sökning: "PCB126"

Hittade 4 avhandlingar innehållade ordet PCB126.

  1. 1. Molecular and phenotypical toxicological effects of environmental pollutants and their mixtures : A mechanistic approach

    Författare :Greta Nilén; Steffen Keiter; Maria Larsson; Nikolai Scherbak; Magnus Engwall; Malin Celander; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Environmental pollutants; mixtures; soil; zebrafish; Danio rerio; behavior; gene expression; lipidomics; image analysis; PCB126; PFOS; B[a]P; Arsenic; risk assessment;

    Sammanfattning : Current environmental risk assessment of polluted sites primarily relies on single compound evaluation. However, in the environment, organisms are often exposed to complex mixtures of pollutants. LÄS MER

  3. 2. Experimental Studies of Endocrine Disrupting Compounds in Vascular Cells and Tissues

    Författare :Helén Andersson; Eva Brittebo; Malin Celander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrine disrupting compounds; endothelium; vascular toxicity; Toxicology; Toxikologi;

    Sammanfattning : Epidemiological evidence suggest that exposure to endocrine disrupting compounds (EDCs) is a risk factor for diseases that involves the cardiovascular system but we know little about the mechanisms whereby these compounds can cause injury in the vasculature. The aim of this thesis was to characterize the effects and mechanisms of some EDCs in vascular cells and highly vascularized tissues. LÄS MER

  4. 3. Liver tumour promoting effects by polychlorinated biphenyls

    Författare :Marie Haag Grönlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :tumour promotion; altered hepatic foci; rat liver; PCB; potency; TEF; interactions; antagonism; biologically based cancer growth models; TCDD;

    Sammanfattning : PCBs cause a number of toxic effects and are present in a variety of biological samples including fish, meat and diary products. Cancer is a serious toxic effect by PCBs that has been observed in animal experiments but the knowledge about PCB induced carcinogenicity is still scarce. LÄS MER

  5. 4. Organochlorines and bone : Effects of organochlorines on bone tissue morphology, composition and strength

    Författare :Monica Lind; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Ecotoxicology; Ekotoxikologi;

    Sammanfattning : From results presented during the last decade, it is obvious that the skeleton is a targetorgan for a number of persistent organochlorines. So far, however, little attention hasbeen paid to this subject. LÄS MER