Sökning: "Danio rerio"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden Danio rerio.

  1. 1. Computational methods for assessing chemical risk : focusing on toxicokinetic modelling in zebrafish (danio rerio)

    Författare :Ioana C. Chelcea; Patrik L. Andersson; Timo Hamers; Jessica Legradi; Stefan Örn; Carolina Vogs; Nynke Kramer; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PBTK; Toxicokinetics; Endocrine disruptors; bisphenols; zebrafish; embryo; Toxicology; toxikologi;

    Sammanfattning : New chemicals are constantly produced and large data gaps exist on hazards of currently used industrial chemicals, stressing the need for rapid, ethically sound and cost-efficient hazard assessment methods. Traditional methods for effect assessment based on animal testing, do not meet these requirements and thus the toxicology field has been moving towards the development of new approach methodologies which include in vitro approaches but also computational methods. LÄS MER

  3. 2. Imaging vascular development in zebrafish (Danio rerio)

    Författare :Staffan Nyström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Formation of a functional vascular network is a prerequisite for physiological organ function in vertebrates. Pathological vascularization furthermore plays a role in several human diseases, such as diabetic retinopathy, cardiovascular disease and cancer. LÄS MER

  4. 3. The role of leptin in zebrafish (Danio rerio) : Novel insights into appetite regulation and reproduction

    Författare :Emmanouil Tsakoumis; Monika Schmitz; Tatjana Haitina; Åsa Wallén-Mackenzie; Ana Gómez Peris; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; zebrafish; leptin; appetite; GRN; brain; reproduction; oocyte maturation; ovulation; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : The hormone leptin is a peripheral metabolic signal and an important regulator of energy balance. In mammals, leptin acts on the appetite centers in the hypothalamus, causing anorexigenic functions by inhibiting food intake. It is also considered as a link between the nutritional status and the endocrine reproductive axis. LÄS MER

  5. 4. The toxicity of perfluoroalkyl acids in zebrafish (Danio rerio)

    Författare :Mazhar Ul haq; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Perfluoroalkyl acids (PFAAs) are globally distributed synthetic chemicals. Their unique properties make them widely used, in industry and elsewhere. These are a group of compounds with varying carbon chain lengths and functional groups. The toxicity evaluation of PFAAs is important to better assess their organismal and environmental impact. LÄS MER

  7. 5. Intraspecific divergence and phenotypic plasticity in behavioural profiles of teleost fish

    Författare :Johanna Axling; Svante Winberg; Johan Höjesjö; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; animal personality; phenotypic plasticity; Salmo salar; Danio rerio; activity; boldness; aggression.; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : Behavioural differences between and within individuals can greatly affect the outcome of behavioural studies. In addition, behavioural interactions between individuals can compromise the health and welfare of captive fish. LÄS MER