Sökning: "Organic chemistry Organisk kemi Naturvetenskap Natural science Quinolone Flavone Pharmacophore GABA"

Hittade 1 avhandling innehållade orden Organic chemistry Organisk kemi Naturvetenskap Natural science Quinolone Flavone Pharmacophore GABA.

1. 1. Pharmacophore Refinement and Lead Optimization - A study of the benzodiazepine site of the GABAA receptors

   Författare :Erik Lager; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; Naturvetenskap; Natural science; Quinolone; Flavone; Pharmacophore; GABA; Benzodiazepine;

   Sammanfattning : Structure activity relationship studies of synthetic flavone derivatives have been utilized to refine and evaluate a pharmacophore model of the benzodiazepine binding site of the GABAA receptors, originally developed by Zhang et al. (Drug Des. Discovery 1995, 12, 193-248). LÄS MER