Sökning: "Oral immunization"
Visar resultat 11 - 15 av 21 avhandlingar innehållade orden Oral immunization.
11. Immune responses related to protection against rotavirus after natural infection and vaccination
Sammanfattning : Rotavirus is the most important cause of severe gastroenteritis in children under five years of age and is estimated to be responsible for one-third of all diarrhea-associated hospitalizations and 600,000 deaths/ year worldwide. 1500-1700 rotavirus-associated hospitalizations of children are estimated to occur annually in Sweden (3. LÄS MER
12. Immune and autoimmune responses to HIV-1 in mucosa and other tissues
Sammanfattning : The aim of these studies was to evaluate routes and devices for administration of HIV-1 DNA vaccines. In particular we were interested in mucosal routes for the induction of immunity at mucosal surfaces. We studied the effects of a novel mucosal route, jet-injection, for induction of systemic and local responses. LÄS MER
13. Immunogenicity and protective potential of Protein D of Haemophilus influenzae against H. influenzae infection
Sammanfattning : Both Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) are important human pathogens causing invasive and mucosal infections. Currently there are number of vaccines available against Hib infections. LÄS MER
14. Regulation of CNS inflammation upon T cell interaction with CNS resident cells
Sammanfattning : Multiple Sclerosis (MS), is a neurologic, autoimmune disease characterized by CNS immune cell infiltration and demyelination. To experimentally study MS, we have utilized the mouse model Experimental Autoimmune Encephalomyelitis (EAE). EAE is induced through immunization with myelin antigens, which elicits an autoreactive Th1 cell response. LÄS MER
15. Cholera toxin B subunit as a carrier for inducing mucosal immunity and/or peripheral tolerance
Sammanfattning : When an antigen is introduced via a mucosal route, either immunity or tolerance, or even both may be induced. Both immunity and tolerance are actively induced phenomena and both of them could have important medical implications as well as potential prophylactic or therapeutic applications. LÄS MER