Sökning: "immunoregulation"

Visar resultat 1 - 5 av 23 avhandlingar innehållade ordet immunoregulation.

  1. 1. Mercury-induced autoimmunity Genetics and immunoregulation

    Detta är en avhandling från Stockholm : Wenner-Grens institut för experimentell biologi

    Författare :Monika Hansson; Stockholms universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mercury; autoimmunity; collagen-induced arthritis; Th1 Th2; silver; tight-skin 1 mice; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi;

    Sammanfattning : The existence of immune self-tolerance allows the immune system to mount responses against infectious agents, but not against self-molecular constitutes. Although self-tolerance is a robust phenomenon, in some individuals as well as in experimental models, the self-tolerance breaks down and as a result, a self-destructive autoimmune disease emerges. LÄS MER

  2. 2. Natural killer T (NKT) lymphocytes regulate of intestinal tumor immunity

    Detta är en avhandling från Stockholm : Wenner-Grens institut för experimentell biologi

    Författare :Ying Wang; Göteborgs universitet.; Gothenburg University.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NKT lymphocyte; intestinal tumor; CD1d; colrectal cancer; immunoregulation; α-gagactosylceramide;

    Sammanfattning : CD1d-restricted natural killer T (NKT) lymphocytes are known as potent early regulatory cells of immune responses, acting as a bridge between innate and adaptive immunity. While invariant NKT (iNKT) cells have a protective role in many tumor models, their ability to promote intestinal inflammation, known to enhance intestinal cancer, raised the question if they would be protective in intestinal tumor development. LÄS MER

  3. 3. Cellular and genetic components in the development of IDDM in NOD mice

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Kristina Lejon; Umeå universitet.; [1996]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-obese diabetic; IgVh gene utilisation; immunoregulation; programmed cell death; genetic linkage analysis; immunologi; Immunology;

    Sammanfattning : .... LÄS MER

  4. 4. C-reactive protein (CRP) and anti-CRP autoantibodies in systemic lupus erythematosus a study on the occurrence and clinical implications of anti-CRP antibodies and CRP-mediated complement activation

    Detta är en avhandling från Institutionen för molekylär och klinisk medicin

    Författare :Christopher Sjöwall; Thomas Skogh; Johan Frostegård; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoantibodies; complement activation; C-reactive protein; cytokines; immune complex; immunoregulation; opsonization; systemic lupus erythematosus; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Rheumatology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Reumatologi;

    Sammanfattning : Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by production of a wide range of autoantibodies, multiple organ involvement and by local formation or tissue deposition of immune complexes (ICs) in the inflamed organs. In contrast to most systemic inflammatory conditions, and despite raised levels of pro-inflammatory cytokines, SLE flares are rarely reflected by elevated C-reactive protein (CRP), an important acute-phase reactant in man with homologs in vertebrates and several invertebrates. LÄS MER

  5. 5. Regulation of CNS inflammation upon T cell interaction with CNS resident cells

    Detta är en avhandling från Ingrid Teige, I11 BMC, 221 84 Lund

    Författare :Ingrid Teige; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurofysiologi; neuropsykologi; Neurologi; neurophysiology; neuron; glia; CNS; T cell; cytokine; immunoregulation; MS; EAE;

    Sammanfattning : Multiple Sclerosis (MS), is a neurologic, autoimmune disease characterized by CNS immune cell infiltration and demyelination. To experimentally study MS, we have utilized the mouse model Experimental Autoimmune Encephalomyelitis (EAE). EAE is induced through immunization with myelin antigens, which elicits an autoreactive Th1 cell response. LÄS MER