Sökning: "UCP1"
Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet UCP1.
1. Modulators of UCP1-dependent thermogenesis : Glucocorticoids, diet and novel research models
Sammanfattning : The activation and recruitment of brown adipose tissue (BAT) thermogenesis has been put forward as a promising strategy to reduce the disease burden of obesity and obesity-related diseases. Heat production by BAT can be attributed to the tissue-specific mitochondrial uncoupling protein 1 (UCP1). LÄS MER
2. Energy flow and metabolic efficiency attributed to brown adipose tissue
Sammanfattning : The large capacity of brown adipose tissue (BAT) to expend energy as heat makes it an interesting potential player in weight regulation and other metabolic conditions. This is of particular interest as it has been recognized that adult humans possess BAT. LÄS MER
3. Genetic Analysis of Fat Metabolism in Domestic Pigs and their Wild Ancestor
Sammanfattning : The domestication of the pig began about 9 000 years ago and many of the existing domestic breeds have been selected for phenotypic traits like lean meat and fast growth. Domestic pigs are phenotypically very different from the ancestral wild boar that has adapted to survive in their natural environment. LÄS MER
4. Regulatory Factors that Reveal Three Distinct Adipocytes : The Brown, the White and the Brite
Sammanfattning : Adipose tissues have long been considered to derive from a common origin. Even the functionally different brown and white adipose tissues were generalized to share a common origin. Brown adipose tissue is a highly innervated and vascularised tissue containing multilocular and multimitochondrial brown adipocytes. LÄS MER
5. Brown is the new white: consequences of white adipose tissue alterations in Huntington's disease
Sammanfattning : Huntington's disease (HD) is a devastating, inherited neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Peripheral symptoms, such as skeletal muscle wasting, progressive weight loss, altered body composition and endocrine disturbances exist alongside neurodegeneration. LÄS MER