Sökning: "NLRP3"

Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet NLRP3.

  1. 1. Innate immunity in human atherosclerosis and myocardial infarction Role of CARD8 and NLRP3

    Detta är en avhandling från Örebro : Örebro University

    Författare :Geena Paramel Varghese; Örebro universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Inflammasome; NLRP3; CARD8; Myocardial infarction; Endothelial cells; Polymorphism; IL-1β; Cytokines; Innate immunity; Biomedicin; Biomedicine;

    Sammanfattning : Atherosclerosis is complex inflammatory disease of the arterial wall with progressive accumulation of lipids and narrowing of the vessel. Increasing evidence suggest that inflammation plays an important role in plaque stability and often accelerate cardiovascular events such as myocardial infarction (MI). LÄS MER

  2. 2. Staphylococcus aureus bacteremia, molecular epidemiology and host immune response

    Detta är en avhandling från Örebro : Örebro University

    Författare :Gunlög Rasmussen; Örebro universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Staphylococcus aureus; molecular epidemiology; DNAmicroarray; bacteremia; sepsis; NLRP3; inflammasome; caspase-1; HLA-DR; HLA-DRA; CD74;

    Sammanfattning : Staphylococcus aureus is a major pathogen responsible for a considerable disease burden worldwide. It may cause a wide array of infections, from superficial skin infections to invasive bacteremia and complications such as infective endocarditis (IE) and osteomyelitis. This thesis aimed to investigate aspects of the molecular epidemiology of S. LÄS MER

  3. 3. Genetic Variations in the NLRP3 Inflammasome Susceptibility Factor for Chronic Inflammation

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Deepti Verma; Linköpings universitet.; Linköpings universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : NLRP3 has been recognized as one of the key components of innate immunity. Upon activation, NLRP3 forms a multiprotein complex called as the ‘inflammasome’ which leads to the activation of pro-inflammatory caspase-1 which subsequently results in the formation of Interleukin (IL)-1β and IL-18. LÄS MER

  4. 4. Dental acrylates and methacrylates - Interactions with the immune system

    Detta är en avhandling från Göteborg : University of Gothenburg. Sahlgrenska Academy, Institute of Odontology

    Författare :Sara Alizadehgharib; Göteborgs universitet.; Gothenburg University.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acrylates; Methacrylates; Antibodies; NLRP3 inflammasome; Cytokines; Mice; Hydrogen sulfide;

    Sammanfattning : Professionals working in dentistry have reported adverse effects, such as allergic contact dermatitis due to exposure to different methacrylates/acrylates. Leakage of such monomers from dental fillings due to incomplete curing is also common. LÄS MER

  5. 5. Importance of bacterial hydrogen sulfide in the pathogenesis of periodontal diseases

    Detta är en avhandling från Göteborg : University of Gothenburg. Sahlgrenska Academy, Institute of Odontology

    Författare :Amina Basic; Göteborgs universitet.; Gothenburg University.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hydrogen sulfide; Periodontitis; Gingivitis; IL-1β; IL-18; NLRP3 inflammasome; Oral microbiota; Fusobacterium spp.; Bismuth test; L-cysteine;

    Sammanfattning : Hydrogen sulfide (H2S) is one of many end-products of the proteolytic activities in the subgingival microbiota in patients with periodontal diseases, such as gingivitis and periodontitis. Although H2S is generally regarded as toxic, the mechanisms that underlie its production and its effects on human cells and tissues are poorly understood. LÄS MER