Sökning: "Kristoffer Strålin"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Kristoffer Strålin.

  1. 1. Diagnostic methods for bacterial etiology in adult community-acquired pneumonia

    Författare :Kristoffer Strålin; Åke Örtqvist; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The etiologic agent is often unidentified in patients with community-acquired pneumonia (CAP). Development of new diagnostic methods has been encouraged. We aimed to develop a multiplex PCR (mPCR) assay for common bacterial pathogens and evaluate the diagnostic usefulness of this assay and of respiratory culture in CAP. LÄS MER

  3. 2. PCR detection of Streptococcus pneumoniae and Haemophilus influenzae in pneumonia patients

    Författare :Guma M. K. Abdeldaim; Björn Herrmann; Jonas Blomberg; Kristoffer Strålin; Birgitta Henriques; Uppsala universitet; []
    Nyckelord :Lower respiratory tract infections; Pneumonia; Streptococcus pneumoniae; Haemophilus influenzae; real-time PCR;

    Sammanfattning : PCR is a rapid, reproducible method for nucleic acid detection. However, this technology displays significant deficiencies when applied in clinical microbiology. This work’s aim was to improve current diagnostics and provide sensitive and quantitative real-time PCRs. LÄS MER

  4. 3. Detection of polysaccharides and polysaccharide antibodies in pneumococcal pneumonia

    Författare :Simon Athlin; Kristoffer Strålin; Hans-Christian Slotved; Hans Fredlund; Kristian Riesbeck; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus pneumoniae; pneumococcus; pneumonia; cellwall polysaccharide; capsular polysaccharide; antibody urinary antigen; nasopharyngeal aspirate; antibody; immunoglobulin; adult; Medicine; Medicin;

    Sammanfattning : .... LÄS MER

  5. 4. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis

    Författare :Sara Cajander; Jan Källman; Kristoffer Strålin; Bo Söderquist; Per Åkesson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; monocyte HLA-DR; sepsis; immunosuppression; bloodstream infection; HLA-DRA; CIITA; qRT-PCR;

    Sammanfattning : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. LÄS MER

  7. 5. Staphylococcus aureus bacteremia, molecular epidemiology and host immune response

    Författare :Gunlög Rasmussen; Bo Söderquist; Kristoffer Strålin; Eva Särndahl; Peter Bergman; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Staphylococcus aureus; molecular epidemiology; DNAmicroarray; bacteremia; sepsis; NLRP3; inflammasome; caspase-1; HLA-DR; HLA-DRA; CD74;

    Sammanfattning : Staphylococcus aureus is a major pathogen responsible for a considerable disease burden worldwide. It may cause a wide array of infections, from superficial skin infections to invasive bacteremia and complications such as infective endocarditis (IE) and osteomyelitis. This thesis aimed to investigate aspects of the molecular epidemiology of S. LÄS MER