Sökning: "Hal Hoffman"

Hittade 1 avhandling innehållade orden Hal Hoffman.

  1. 1. Genetic Variations in the NLRP3 Inflammasome : Susceptibility Factor for Chronic Inflammation

    Författare :Deepti Verma; Peter Söderkvist; Särndahl Särndahl; Hal Hoffman; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : NLRP3 has been recognized as one of the key components of innate immunity. Upon activation, NLRP3 forms a multiprotein complex called as the ‘inflammasome’ which leads to the activation of pro-inflammatory caspase-1 which subsequently results in the formation of Interleukin (IL)-1β and IL-18. LÄS MER