Sökning: "Lon protease"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Lon protease.

  1. 1. Regulated Proteolysis: The Secrets of Lon : Cellular Roles and Stress-dependent Regulation of the Lon Protease

    Författare :Matthias J. Fink; Kristina Jonas; Axel Mogk; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Lon protease; regulated proteolysis; allosteric regulation; Caulobacter crescentus; stress responses; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Proteolysis is crucial in cells to maintain a functional proteome. It is required for removal of damaged and unfolded proteins during protein quality control, and serves as a mechanism to regulate protein levels through regulated proteolysis. LÄS MER

  3. 2. Structural-functional studies of mitochondrial matrix proteins

    Författare :Saba Shahzad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mitochondria;

    Sammanfattning : The mitochondrion is the powerhouse of the eukaryotic cell. Most of the energy required to carry out cellular processes is generated inside mitochondria via the process of oxidative phosphorylation. The machinery required for oxidative phosphorylation is encoded by both the nuclear and the mitochondrial genome. LÄS MER

  4. 3. On the molecular mechanism of LHCII proteolysis during photoacclimation of photosystem II

    Författare :Dan-Hui Yang; Peter Horton; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : Higher plants and green algae have a remarkable ability to respond to fluctuations in the light intensity. Plants adapted to low or high light regimes possess larger or smaller light-harvesting antennae respectively. LÄS MER

  5. 4. Studies of enzymes in mitochondrial DNA precursor synthesis : regulatory mechanisms for human thymidine kinase 2 and deoxyguanosine kinase

    Författare :Ren Sun; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : As important enzymes in mitochondrial nucleotide salvage pathway, thymidine kinase 2 (TK2) and deoxyguanosine kinase (dGK) are expressed constitutively in almost all cells. These two enzymes catalyze the initial rate-limiting phosphorylation of pyrimidine and purine deoxynucleosides, respectively, providing DNA precursors for mitochondrial DNA (mtDNA) replication. LÄS MER

  7. 5. Into the Membrane and Beyond : Improving Membrane Protein Over-Expression in Escherichia coli

    Författare :Mirjam Klepsch; Jan-Willem de Gier; Reinhard Grisshammer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; membrane protein over-expression; proteomics; T7 RNA polymerase; peptide transport; strain engineering; Biochemistry; Biokemi; Biophysical chemistry; Biofysikalisk kemi; biokemi; Biochemistry;

    Sammanfattning : Membrane proteins fulfil a wide variety of essential functions in the cell and many are (potential) drug targets. Since their natural abundance is usually very low, most membrane proteins have to be over-expressed for functional and structural studies. LÄS MER