Sökning: "Lipid self-assembly"

Visar resultat 16 - 20 av 32 avhandlingar innehållade orden Lipid self-assembly.

1. 16. Aggregation behavior and peptide-lipid interaction in an amyloid model system

   Författare :Jon Pallbo Arvidsson; Fysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; amyloids; peptides; lipids; NACore; aggregation; fibrillation; crystallization; self-assembly; interaction;

   Sammanfattning : Proteins constitute a major component of living cells and are essential to their function. Sometimes proteins misfold or aggregate in abnormal ways, which can give rise to diseases. Amyloids are a special type of highly ordered protein aggregates made of long intermolecular beta-sheets stacked into fibrils. LÄS MER

3. 17. Small-Scale Sample Handling for Studies of Liquid Crystals and Lipid-Based Soft Matter

   Författare :Gabriel Ohlsson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorescence microscopy; nanocell; Microfluidics; aquaporins; liquid crystals; membrane transport; phase transitions; QCM-D; soft matter; lipid bilayer;

   Sammanfattning : In the field of sensing in general and biosensing in particular, there is a growing need for integratingminiaturised senor elements in microfluidic systems. The advantages are several, some of which being that the consumption of, often very expensive, sample material can be reduced; sampleexchange can be optimized; sensor performance in terms of detection limits can be improved and phenomena occurring on a very small, and even single-molecule, scale can be studied. LÄS MER

4. 18. Supported Lipid Membranes and Their Use for the Characterization of Biological Nanoparticles

   Författare :Silver Jõemetsa; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fluorescence microscopy; supported lipid bilayer; lipophilic dyes; size determination; diffusion; microfluidics;

   Sammanfattning : Biological nanoparticles (BNPs) are nano-sized lipid vesicles of biological origin, which are involved in multiple biological processes. BNP characterization techniques are critical for improving the understanding of how these particles contribute to cellular communication, viral infections and drug-delivery applications. LÄS MER

5. 19. Advances in Soft Matter Nanofabrication

   Författare :Mehrnaz Shaali; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; photolithography; negative e-beam resist; monolayer; confocal microscopy; Teflon AF; KPFM; DNA origami; cells; lipid nanotube; AFM; double bilayer; Phospholipid; electron beam lithography;

   Sammanfattning : The focus of this thesis is placed on the fabrication of engineered nanodevices for the manipulation of soft matter thin films. By combining top-down micro- and nanofabrication approaches with bottom-up self-assembly strategies, new research platforms were developed, tested and characterized. LÄS MER

7. 20. Fluorescent Probes and Protein Misfolding: Methods and Applications

   Författare :Irem Nasir; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein misfolding; fluorophores; filter-trap; site-specific fluorophore labeling; amyloid-beta; microscopic rate constants; solvatochromic probes; alpha-synuclein; lipid vesicles; nanoparticles; protein adsorption;

   Sammanfattning : Protein misfolding is a frequently occurring event in living cells and without the quality control, the consequences are disasterous. In this thesis, we studied protein misfolding in vitro by employing a variety of fluorophores, to either detect the highly ordered aggregates of intrinsically disordered proteins/peptides or slight misfolding of a natively folded protein. LÄS MER