Sökning: "Lipid self-assembly"

Visar resultat 6 - 10 av 32 avhandlingar innehållade orden Lipid self-assembly.

  1. 6. Lipid Vesicle Fusion: Investigation, Generation and Manipulation of Cell-Membrane Mimics

    Författare :Lisa Simonsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; diffusion; spreading lipid bilayers; cell mimic; micromanipulation; lipid bilayer; microfluidics; site-specificity; DNA; membrane-receptor interactions; total internal reflection fluorescence microscopy; model system; self-assembly; TIRF microscopy; FRET; exocytosis; vesicles; fluorescence resonance energy transfer; biomembranes; amperometry; membrane fusion;

    Sammanfattning : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. In this work, cell-membrane mimics were constructed and evaluated as models for studies of the membrane-fusion process. LÄS MER

  3. 7. Unravelling the structure and dynamics of lipid nanoparticles for biomolecule delivery

    Författare :Jennifer Gilbert; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; lipid nanoparticles; neutron scattering; SAXS; protein encapsulation; nucleic acid delivery; lipid self-assembly;

    Sammanfattning : Encapsulation in self-assembled lipid structures has been shown to increase the stability of large biomolecules, including proteins and nucleic acids (NAs), which has many potential applications in the food and pharmaceutical industries. In order to fully optimise the encapsulation system for a certain application, however, it is important to understand the effect of the encapsulated biomolecule on the lipid structure and vice versa. LÄS MER

  4. 8. Bottom-up Fabrication of Functional DNA Nanostructures

    Författare :Erik Lundberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; click chemistry; gel electrophoresis; self-assembly; cross-linking; lipid membrane; fixation; linear dichroism; nanotechnology; spectroscopy; fret; dna; triplex recognition;

    Sammanfattning : This thesis demonstrates bottom-up fabrication of a fully addressable non-repetitive network on the nanometer scale, assembled by synthetic DNA molecules. Each side constitutes a unique sequence of 10 bases, i.e. 3. LÄS MER

  5. 9. First As Probe, Then As Function - Fluorescence in Bio-inspired Nanotechnology

    Författare :Jonas Hannestad; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; self-assembly; lipid membrane; bio-inspired; FRET; light-harvesting; spectroscopy.; fluorescence; nanotechnology; single molecule fluorescence spectroscopy; DNA;

    Sammanfattning : In this thesis, I demonstrate how fluorescence can be used in the context of bio-inspired nanotechnology, both as an indirect probe and as a function in itself. By combining principles and molecules from three different bio-molecular systems, DNA, bacterial light-harvesting complexes and cell membranes, I have constructed nano- and microscale systems for long-range excitation energy transfer, light-harvesting and reaction control. LÄS MER

  7. 10. Building Blocks for the Assembly of Nanostructures

    Författare :Tina Gschneidtner; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molecules; Self-Assembly; sensing; nanoparticles; plasmon;

    Sammanfattning : The natural world and many man made technologies are driven by self-assembly, involving the autonomous organization of individual components as a result of specific local interactions into functional structures. Self-assembly is a platform from which to construct materials with a high complexity, in high precision, with an inbuilt error- correction system due to its dynamic nature. LÄS MER