Sökning: "lipid vesicles"
Visar resultat 1 - 5 av 145 avhandlingar innehållade orden lipid vesicles.
1. Tethered Lipid Vesicles as Nanoscale Sensor Elements
Sammanfattning : The primary aim of this thesis work has been to explore and advance the potential of surface tethered lipid vesicles as a platform for studying in particular the following three biomembrane-related processes: trans-membrane transport, membrane-peptide interactions and the activity of membrane active enzymes. First, a method based on surface plasmon resonance (SPR) spectroscopy was developed for studying passive diffusion processes as well as the membrane-protein mediated transport of small non electrolyte molecules across lipid bilayers. LÄS MER
2. Formation of Block Copolymer and Surfactant Vesicles
Sammanfattning : In this thesis temperature induced vesicle formation in both a block copolymer system and nonionic surfactant system have been investigated. The block copolymer is a triblock copolymer of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), PEO-PPO-PEO, with the average molecular composition of EO5PO68EO5 and the commercial trade name Pluronic L121 (papers I, II). LÄS MER
3. Membrane-Polymer Interactions in Lipid Vesicles
Sammanfattning : Membrane related biological processes are commonly investigated in artificial biomimetic experimental systems. One of the most versatile models is based upon giant unilamellar phospholipid vesicles (liposomes), which are artificially generated spherical lipid structures in an aqueous environment. LÄS MER
4. DNA-Controlled Lipid-Membrane Fusion
Sammanfattning : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. We have demonstrated that short DNA oligonucleotides, membrane-attached via CH in an orientation that mimics the overall zipperlike architecture of fusion-inducing proteins, induce fusion of both suspended vesicles and vesicles site-specifically tethered to SLBs. LÄS MER
5. Lipid Vesicle Fusion: Investigation, Generation and Manipulation of Cell-Membrane Mimics
Sammanfattning : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. In this work, cell-membrane mimics were constructed and evaluated as models for studies of the membrane-fusion process. LÄS MER