Sökning: "L Wide"

Visar resultat 16 - 20 av 178 avhandlingar innehållade orden L Wide.

  1. 16. Specification Decomposition and Formal Behavior Generation in Multi-Robot Systems

    Författare :Philipp Schillinger; Dimos V. Dimarogonas; Mathias Bürger; Stephen L. Smith; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Multi-Robot Systems; Linear Temporal Logics; LTL; Robotics; Behavior Synthesis; Constrained Planning; Planning under Uncertainty; Multi-Agent Planning; Task Allocation; Mission Decomposition; Formal Methods; Electrical Engineering; Elektro- och systemteknik;

    Sammanfattning : Autonomous robot systems are becoming increasingly common in service applications and industrial scenarios. However, their use is still mostly limited to rather simple tasks. This primarily results from the considerable effort that is required to manually program the execution plans of the robots. LÄS MER

  3. 17. Chemical perspectives on aerosol-cloud interactions in the High Arctic

    Författare :Karolina Siegel; Claudia Mohr; Annica M. L. Ekman; Ilona Riipinen; Ryan Sullivan; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Aerosol chemical composition; DMS oxidation; FIGAERO-CIMS; κ-Köhler theory; High Arctic; Atmospheric Sciences and Oceanography; atmosfärvetenskap och oceanografi;

    Sammanfattning : Atmospheric aerosol particles have important yet highly uncertain impacts on the Earth’s climate, with the largest uncertainties residing in the interactions between aerosols and clouds. The extent to which aerosols act as cloud condensation nuclei (CCN) depends on the chemical composition and size of the particles. LÄS MER

  4. 18. Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver

    Författare :Magnus Ölander; Per Artursson; Pär Matsson; Edward L. LeCluyse; Volker Lauschke; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; drug disposition; ADMET; drug transport; drug metabolism; hepatotoxicity; small intestine; liver; caco-2; human hepatocytes; cryopreservation; apoptosis; liver zonation; non-parenchymal cells; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : To reach the bloodstream, an orally administered drug must be absorbed through the small intestine and avoid extensive clearance in the liver. Estimating these parameters in vitro is therefore important in drug discovery and development. LÄS MER

  5. 19. Multi-platform metabolomics assays to study the responsiveness of the human plasma and lung lavage metabolome

    Författare :Masoumeh Karimpour; Malin Nording L.; Magnus Åberg; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LC MS; GC MS; NMR; metabolomics; metabolite; exposure; postprandial; plasma; lung lavage; BW; BW; data analysis; univariate analysis; multivariate analysis;

    Sammanfattning : Metabolomics as a field has been used to track changes and perturbations in the human body by investigating metabolite profiles indicating the change of metabolite levels over time and in response to different challenges. In this thesis work, the main focus was on applying multiplatform-metabolomics to study the human metabolome following exposure to perturbations, such as diet (in the form of a challenge meal) and exhaust emissions (air pollution exposure in a controlled setting). LÄS MER

  7. 20. Metabolomics studies of ALS : a multivariate search for clues about a devastating disease

    Författare :Anna Wuolikainen; Peter M Andersen; Henrik Antti; Stefan L Marklund; Thomas Moritz; Thomas Hankemeier; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyotrophic lateral sclerosis ALS ; motor neuron disease; Lou Gehrig’s disease; human disease; CSF; biomarkers; metabolomics; metabonomics; chemometrics; design of experiments; multivariate analysis.; Neurology; Neurologi; Neurology; neurologi;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS), also known as Charcot’s disease, motor neuron disease (MND) and Lou Gehrig’s disease, is a deadly, adult-onset neurodegenerative disorder characterized by progressive loss of upper and lower motor neurons, resulting in evolving paresis of the linked muscles. ALS is defined by classical features of the disease, but may present as a wide spectrum of phenotypes. LÄS MER