Sökning: "lung lavage"

Visar resultat 1 - 5 av 92 avhandlingar innehållade orden lung lavage.

1. 1. Minimally invasive cardiorespiratory monitoring and lung recruitment manoeuvres. Studies in animals and humans

   Författare :Helena Odenstedt; Göteborgs universitet; []
   Nyckelord :Monitoring; cardiac output; lung volume; lung recruitment manoeuvre; regional ventilation; acute lung injury; bronchoalveolar lavage; endotoxin; cardiac tamponade;

   Sammanfattning : Background: The maintenance of adequate oxygen delivery is essential to preserve organ function. The circulatory and respiratory systems interact closely to accomplish this. Optimising the function of these systems is of fundamental importance in critically ill patients. This requires adequate monitoring techniques. LÄS MER

3. 2. Open and closed endotracheal suctioning. Experimental and human studies

   Författare :Sophie Lindgren; Göteborgs universitet; []
   Nyckelord :suctioning; endotracheal; closed system suctioning; monitoring; lung volume; airway pressure; lung recruitment; bronchoalveolar lavage; acute lung injury;

   Sammanfattning : Background: The practice of endotracheal suctioning of ventilator treated patients is necessary to remove secretions to prevent obstruction of the endotracheal-tracheal tube and lower airways. This very common procedure creates a large variety of heart-lung interferences. LÄS MER

4. 3. The Immune Response to One-Lung Ventilation : Clinical and Experimental Studies

   Författare :Thomas Schilling; Göran Hedenstierna; Hans Hedenström; Thomas Hachenberg; Sven-Erik Ricksten; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; Medical laboratory science; Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

   Sammanfattning : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. LÄS MER

5. 4. Titrating Open Lung PEEP in Acute Lung Injury : A clinical method based on changes in dynamic compliance

   Författare :Fernando Suarez Sipmann; Göran Hedenstierna; Hans Hedenström; Stefan Lundin; Uppsala universitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; PEEP; open lung; recruitment; dead space; electrical impedance tomography; ARDS.; Medicine; Medicin;

   Sammanfattning : The recognition that supportive mechanical ventilation can also damage the lung, the so called ventilation induced lung injury (VILI), has revived the more than 40 year long debate on the optimal level of PEEP to be used. It is established that the prevention of VILI improves patient outcome and that PEEP exerts protective effects by preventing unstable diseased alveoli from collapsing. LÄS MER

7. 5. Multi-platform metabolomics assays to study the responsiveness of the human plasma and lung lavage metabolome

   Författare :Masoumeh Karimpour; Malin Nording L.; Magnus Åberg; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LC MS; GC MS; NMR; metabolomics; metabolite; exposure; postprandial; plasma; lung lavage; BW; BW; data analysis; univariate analysis; multivariate analysis;

   Sammanfattning : Metabolomics as a field has been used to track changes and perturbations in the human body by investigating metabolite profiles indicating the change of metabolite levels over time and in response to different challenges. In this thesis work, the main focus was on applying multiplatform-metabolomics to study the human metabolome following exposure to perturbations, such as diet (in the form of a challenge meal) and exhaust emissions (air pollution exposure in a controlled setting). LÄS MER