Sökning: "lung lavage"
Visar resultat 1 - 5 av 79 avhandlingar innehållade orden lung lavage.
1. Minimally invasive cardiorespiratory monitoring and lung recruitment manoeuvres. Studies in animals and humans
Sammanfattning : Background: The maintenance of adequate oxygen delivery is essential to preserve organ function. The circulatory and respiratory systems interact closely to accomplish this. Optimising the function of these systems is of fundamental importance in critically ill patients. This requires adequate monitoring techniques. LÄS MER
Sammanfattning : Background: The practice of endotracheal suctioning of ventilator treated patients is necessary to remove secretions to prevent obstruction of the endotracheal-tracheal tube and lower airways. This very common procedure creates a large variety of heart-lung interferences. LÄS MER
- Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis
Sammanfattning : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. LÄS MER
4. Titrating Open Lung PEEP in Acute Lung Injury A clinical method based on changes in dynamic complianceDetta är en avhandling från Uppsala : Acta Universitatis Upsaliensis
Sammanfattning : The recognition that supportive mechanical ventilation can also damage the lung, the so called ventilation induced lung injury (VILI), has revived the more than 40 year long debate on the optimal level of PEEP to be used. It is established that the prevention of VILI improves patient outcome and that PEEP exerts protective effects by preventing unstable diseased alveoli from collapsing. LÄS MER
5. Multi-platform metabolomics assays to study the responsiveness of the human plasma and lung lavage metabolomeDetta är en avhandling från Umeå : Umeå University
Sammanfattning : Metabolomics as a field has been used to track changes and perturbations in the human body by investigating metabolite profiles indicating the change of metabolite levels over time and in response to different challenges. In this thesis work, the main focus was on applying multiplatform-metabolomics to study the human metabolome following exposure to perturbations, such as diet (in the form of a challenge meal) and exhaust emissions (air pollution exposure in a controlled setting). LÄS MER