Sökning: "Thomas Moritz"
Hittade 5 avhandlingar innehållade orden Thomas Moritz.
Sammanfattning : Amyotrophic lateral sclerosis (ALS), also known as Charcot’s disease, motor neuron disease (MND) and Lou Gehrig’s disease, is a deadly, adult-onset neurodegenerative disorder characterized by progressive loss of upper and lower motor neurons, resulting in evolving paresis of the linked muscles. ALS is defined by classical features of the disease, but may present as a wide spectrum of phenotypes. LÄS MER
Sammanfattning : A trend in natural science and especially in analytical chemistry is the increasing need for analysis of a large number of complex samples with low analyte concentrations. Biological samples (urine, blood, plasma, cerebral spinal fluid, tissue etc. LÄS MER
3. Selectivity in NMR and LC-MS Metabolomics : The Importance of Sample Preparation and Separation, and how to Measure Selectivity in LC-MS Metabolomics
Sammanfattning : Until now, most metabolomics protocols have been optimized towards high sample throughput and high metabolite coverage, parameters considered to be highly important for identifying influenced biological pathways and to generate as many potential biomarkers as possible. From an analytical point of view this can be troubling, as neither sample throughput nor the number of signals relates to actual quality of the detected signals/metabolites. LÄS MER
Sammanfattning : The human being and other animals contain immensely complex biochemical processes that govern their function on a cellular level. It is estimated that several thousand small molecules (metabolites) are produced by various biochemical pathways in humans. LÄS MER
Sammanfattning : Multi-tissue metabolomics involves characterisation of the metabolome of several tissue types. The metabolome consists of small chemical entities of low molecular weight called metabolites, which are constantly produced and interchanged through a vast variety of biochemical reactions occurring throughout living organisms. LÄS MER