Sökning: "Ion transporters"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden Ion transporters.

1. 1. Expression and regulation of water channels and ion transporters : ontogenic aspects

   Författare :Masato Yasui; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :water balance; developmental gene expression regulation; gene transcription; fetal lung fluid; urinary concentrating capacity; hormonal regulation;

   Sammanfattning : The content and distribution of body water changes dramatically during the perinatal period and in infancy. Transport of water across the cell membrane occurs via diffusion and via specific water channels. Transport via water channels is fast and may be hormonally regulated. LÄS MER

3. 2. Applying the Pump and Leak Hypothesis. An experimental and theoretical investigation of the principles of ion regulation and excitability in the crustacean stretch receptor neuron

   Författare :Sten Theander; Människan i rörelse: hälsa och rehabilitering; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; lobster; stretch receptor neuron; leak current; Q-current; K-Cl cotransporter; A-current; mathematical model; excitability; GABA channel; neurophysiology; ion regulation; neuropsykologi; Neurologi; neurofysiologi;

   Sammanfattning : An invertebrate nerve cell preparation, the lobster stretch receptor neuron, was investigated with respect to maintenance of its resting voltage, intracellular ion concentrations and excitability using voltage clamp technique and ion-selective microelectrodes. It was found that the resting voltage (-65 mV) of microelectrode impaled cells is caused by (a) a homogenous population of K+ channels which we denoted as leak channels (b) an electrogenic and voltage-dependent Na-K pump current and (c) an inward microelectrode-induced "impalement" current carried mainly by Na+. LÄS MER

4. 3. Ion homeostasis in control of stem cell proliferation

   Författare :Shaimaa Abdelhady; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The ion homeostasis is critically maintained in all cells by a combined effort from various ion channels, transporters, pumps, and gap junctions. Ion fluxes are essential in excitable cells as they regulate the excitability of the cells and initiate and propagate action potentials. LÄS MER

5. 4. Understanding structure and function of membrane protein transporters

   Författare :Anna-Karin Lundbäck; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Membrane protein transporters are important proteins in the cell, as they maintain different solutes and metabolites at a stable concentration. Numerous diseases can be linked to malfunctioning transporters, which makes them interesting pharmaceutical targets. LÄS MER

7. 5. Elucidating the molecular basis of Na+/H+ exchange

   Författare :Pascal F. Meier; David Drew; Simon Newstead; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane protein; secondary-active transporter; Solute Carrier Transporter; ion-exchange; sodium proton exchanger; potassium proton exchanger; protein structure; cryo-EM; regulation; biokemi; Biochemistry;

   Sammanfattning : Solute carrier (SLC) transporters are membrane transport proteins, which catalyse the movement of nutrients, ions, and drugs across cell membranes. Here, I will present our contribution to understanding the mechanism of the sodium/proton exchangers (NHE), belonging to the SLC9 family of membrane transporters. LÄS MER