Sökning: "Intracellular K content"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Intracellular K content.

  1. 1. Genetic re-targeting of adenoviral vectors for gene therapy applications

    Författare :Maria K Magnusson; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : The adenovirus (Ad) is a frequent cause of upper respiratory tract infections, enteritis and conjunctivitis. Since its first isolation in 1953, the study of Ad has contributed greatly to the understanding of intracellular events and has also served as a model system for many viruses. LÄS MER

  3. 2. Cellular responses to amyloid-beta protofibrils : Focus on astrocytes, extracellular vesicles and antibody treatment

    Författare :Elisabeth Nikitidou; Anna Erlandsson; Martin Ingelsson; Gunnar K. Gouras; Uppsala universitet; []
    Nyckelord :Alzheimer’s disease; Amyloid-beta; Protofibrils; Astrocytes; Extracellular vesicles; Antibody; Neurons; Degradation; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Knowledge about the cellular mechanisms behind the initiation and propagation of Alzheimer’s disease (AD) is limited. Decades of research have focused on neuronal abnormalities in AD, but recently more attention has been given to the glial cells. LÄS MER

  4. 3. Manipulation of potassium ion fluxes to induce apoptosis in lung cancer cells

    Författare :Britta Andersson; Kjell Grankvist; Parviz Behnam-Motlagh; Roger Henriksson; Ola Brodin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; Cisplatin; Intracellular K content; Mesothelioma; Na K ATPase pump; Clinical chemistry; Klinisk kemi;

    Sammanfattning : Apoptosis is a special form of cell death that if non-functional may lead to diseases such as cancer. A reduction of the intracellular potassium ion (K+) content is necessary for activating enzymes important for the execution of apoptosis. LÄS MER

  5. 4. Corticosteroid receptors and Na,K-ATPase in the developing mouse cochlea

    Författare :Susan Erichsen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :inner ear; stria vascularis; endolymph production; Na; K-ATPase; glucocorticoid receptor; mineralocorticoid receptor; knockout mouse; shaker-2; mix; immunohistochemistry;

    Sammanfattning : The senses of hearing and equilibrium are highly dependent on the fluid and electrolyte homeostasis in the inner ear. The characteristic intracellular-like ionic composition of endolymph fluid in relation to the surrounding perilymph creates the endocochlear potential (EP), which is a prerequisite for inner ear function. LÄS MER

  7. 5. Gene regulation, intracellular signaling and membrane traffic : studies in primary human skeletal muscle cultures

    Författare :Lubna Al-Khalili; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Skeletal muscle cultures; insulin signal transduction; glucose transport; GLUT4; RNAi; Na ; K -ATPase; MEF2;

    Sammanfattning : Skeletal muscle is an insulin sensitive organ and plays a major role in whole body electrolyte and substrate homeostasis in the post prandial state. Impaired insulin action in skeletal muscle may lead to the pathological condition of insulin resistance. LÄS MER