Sökning: "Hypervalent iodine"

Visar resultat 6 - 10 av 19 avhandlingar innehållade orden Hypervalent iodine.

  1. 6. Synthesis of Organofluorine Compounds and Allenylboronic Acids - Applications Including Fluorine-18 Labelling

    Författare :Denise N. Meyer; Kálmán J. Szabó; Dominique Cahard; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; boron; allenylboronic acid; BINOL; homopropargyl alcohol; organocatalyst; organoboron; organofluorine; fluorine; fluorine-18; late-stage; labelling; labeling; nucleophilic; electrophilic; fluorination; positron emision tomography; PET; radiotracer; hypervalent iodine; benziodoxole; benzoxazepines; diaryliodonium salt; metal-free; neutrophil elastase; NE; neutrophil elastase inhibitor; trifluoromethylation; trifluoromethylthiolation; difluoro enol silyl ethers; organisk kemi; Organic Chemistry;

    Sammanfattning : This work is focused on two areas: the chemistry of organofluorine and organoboron compounds. In the first chapter, a copper-catalysed synthesis of tri- and tetrasubstituted allenylboronic acids is presented. Extension of the same method leads to allenylboronic esters. LÄS MER

  3. 7. Diaryliodonium Salts : Synthesis, Applications and Computational Investigations

    Författare :Marcus Reitti; Berit Olofsson; Michael Greaney; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; diaryliodonium salt; hypervalent iodine; density functional theory; aryne; phenol; nitroarene; organisk kemi; Organic Chemistry;

    Sammanfattning : Organic chemists have the ability to create complex organic molecules by connecting molecular building blocks in different ways. To name a few, these molecules are used as medicines, pesticides or in our household electronics, and are therefore crucial to life as we know it. LÄS MER

  4. 8. Transition Metal-Free O-, N- and S-Arylations with Diaryliodonium Salts

    Författare :Gabriella Kervefors; Berit Olofsson; Boris Nachtsheim; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Amines; hypervalent iodine; electrophilic arylation; methodology development; total synthesis; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis concerns the development of metal-free arylation procedures using diaryliodonium salts, a non-toxic and versatile electrophilic arylating reagent, with applications to synthesize biologically relevant targets.The first part describes a transition metal-free formal synthesis of phenoxazine with an O-functionalization of a certain phenol as a key step. LÄS MER

  5. 9. Metal-Free O- and C-Arylation with Diaryliodonium Salts

    Författare :Erik Lindstedt; Berit Olofsson; Kilian Muñiz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hypervalent Iodine; Alkyl Aryl Ethers; Nitro Compounds; Alcohols; Diaryliodonium Salts; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis concerns the development of metal-free applications using diaryliodonium salts. The first project describes an arylation protocol of allylic and benzylic alcohols in aqueous media. The method proceeds under mild conditions and the ether products were obtained in moderate to good yields. LÄS MER

  7. 10. Bifunctionalization of Small Organic Molecules Based on Fluorine Incorporation

    Författare :Marvin Lübcke; Kálmán Szabó; Ryan Gilmour; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorination; fluorocyclization; fluorine chemistry; trifluoromethylthiolation; rhodium-catalysis; organocatalysis; asymmetric synthesis; hypervalent iodine; multicomponent reaction; bifunctionalization; diazo compounds; organisk kemi; Organic Chemistry;

    Sammanfattning : The dissertation work that is summarized in this thesis describes novel syntheses of organofluorine compounds with a broad coverage of different fluorine-containing motifs.Chapter 2.1 covers works on the exploration of new trifluoromethylthiolating reactions of diazocarbonyl compounds. LÄS MER