Sökning: "aryne"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet aryne.

  1. 1. Diaryliodonium Salts : Synthesis, Applications and Computational Investigations

    Författare :Marcus Reitti; Berit Olofsson; Michael Greaney; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; diaryliodonium salt; hypervalent iodine; density functional theory; aryne; phenol; nitroarene; organisk kemi; Organic Chemistry;

    Sammanfattning : Organic chemists have the ability to create complex organic molecules by connecting molecular building blocks in different ways. To name a few, these molecules are used as medicines, pesticides or in our household electronics, and are therefore crucial to life as we know it. LÄS MER

  3. 2. New Arylation Strategies Based on Organomain Group Reactivity

    Författare :Carina Sollert; Lukasz T. Pilarski; Brenton L. DeBoef; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; C-H functionalisation; catalysis; ruthenium; indole; silylation; boronate; boryl aryne; aryne distortion; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : The work in this thesis describes the development of new heteroarylation methodology based on transition metal-catalysed C-H functionalisation and the properties of organomain group compounds. The underlying reaction mechanisms and reactivity patterns of the (hetero)arene substrates are also investigated. LÄS MER

  4. 3. Control of Aryne Capture Regioselectivity via Fluoroboronate-induced Distortion

    Författare :Matic Hribersek; Lukasz Pilarski; Carl Johan Wallentin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Arynes are valued as extremely versatile electrophilic intermediates. Control over the regioselectivity with which arynes react is typically achieved using comparatively simple and/or chemically inutile substituents close to the reactive triple bond. LÄS MER

  5. 4. Ruthenium-catalyzed C-H Functionalization of (Hetero)arenes

    Författare :Karthik Devaraj; Lukasz T. Pilarski; Victor A. Snieckus; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; catalysis; C-H activation; heterocycles; ruthenium; aryne precursor; silylation; gramine;

    Sammanfattning : This thesis concerned about the Ru-catalyzed C-H functionalizations on the synthesis of 2-arylindole unit, silylation of heteroarenes and preparation of aryne precursor.In the first project, we developed the Ru-catalyzed C2-H arylation of N-(2-pyrimidyl) indoles and pyrroles with nucleophilic arylboronic acids under oxidative conditions. LÄS MER

  7. 5. New Strategies for Transition Metal-mediated (Hetero)arene Functionalization

    Författare :Fredric Ingner; Lukasz Pilarski; Joanna Wencel-Delord; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis describes new approaches to achieve efficient and selective (hetero)arene derivatization using transition metals. The main focus falls on the use of strategies based on C–H activation and organo-main group reactivity to render the synthesis of various (hetero)arene derivatives more direct, efficient, regioselective and sustainable. LÄS MER