Sökning: "fluorine chemistry"

Visar resultat 1 - 5 av 49 avhandlingar innehållade orden fluorine chemistry.

1. 1. Development of new Fluorination Methods Directed to Fluorine-18 Labelling

   Författare :Miguel Ángel Cortés González; Kálmán J. Szabó; Guosheng Liu; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorine; fluorine-18; late-stage; labelling; nucleophilic; electrophilic; fluorination; positron emision tomography; PET; hypervalent iodine; benziodoxole; metal-free; DBU; copper; palladium; rhodium; carbene; organisk kemi; Organic Chemistry;

   Sammanfattning : This thesis deals with the development of new fluorination reactions and their application to fluorine-18 labelling. Fluorine-18 labelled compounds are employed as tracers in Positron Emission Tomography (PET), which is a powerful non-invasive imaging method in medical diagnostics. LÄS MER

3. 2. Synthesis of Organofluorine Compounds and Allenylboronic Acids - Applications Including Fluorine-18 Labelling

   Författare :Denise N. Meyer; Kálmán J. Szabó; Dominique Cahard; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; boron; allenylboronic acid; BINOL; homopropargyl alcohol; organocatalyst; organoboron; organofluorine; fluorine; fluorine-18; late-stage; labelling; labeling; nucleophilic; electrophilic; fluorination; positron emision tomography; PET; radiotracer; hypervalent iodine; benziodoxole; benzoxazepines; diaryliodonium salt; metal-free; neutrophil elastase; NE; neutrophil elastase inhibitor; trifluoromethylation; trifluoromethylthiolation; difluoro enol silyl ethers; organisk kemi; Organic Chemistry;

   Sammanfattning : This work is focused on two areas: the chemistry of organofluorine and organoboron compounds. In the first chapter, a copper-catalysed synthesis of tri- and tetrasubstituted allenylboronic acids is presented. Extension of the same method leads to allenylboronic esters. LÄS MER

4. 3. Synthesis of Novel Fluorine-Free Salts for Battery Electrolytes

   Författare :Elham Hosseini Bab Anari; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; solid state electrolyte; aqueous electrolyte; lithium-ion batteries LIBs ; safer electrolyte; ionic liquid based electrolyte; water-in-bisalt WiBS electrolyte.; sodium-ion batteries SIBs ; fluorine-free salt;

   Sammanfattning : Nowadays lithium-ion batteries (LIBs) are the dominant power sources of portable electronic devices such as mobile phones, laptops and cameras. Although recently their applications have extended to areas of electromobility and hybridization of vehicle, cost and safety issues remain as big obstacles for a smoother implementation. LÄS MER

5. 4. Multi-functional Hyaluronan Based Biomaterials for Biomedical Applications

   Författare :Xia Yang; Dmitri Ossipov; Matthias Lutolf; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hyaluronan; biomaterials functionalizations; biomedical applications; orthogonal chemistry; drug delivery; tissue regeneration; MRI; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

   Sammanfattning : This thesis presents strategies for constructing multi-functional biomaterials based on hyaluronan (HA) derivatives for various biomedical applications, such as drug delivery, tissue regeneration, and imaging biomaterials. The aim of this study is to improve the functionalities of HA biomaterials as well as simplify the preparation procedures. LÄS MER

7. 5. Development of Palladium-Promoted 11C/12C-Carbonylations and Radiosynthesis of Amyloid PET Ligands

   Författare :Patrik Nordeman; Gunnar Antoni; Mats Larhed; Luke R Odell; Antony D Gee; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Palladium; Carbonylation; Positron emission tomography; PET; Carbon-11; Fluor-18; Radiochemistry; Amyloidosis; Palladium; Karbonyleringar; Positronemissionstomografi; PET; Kol-11; Fluor-18; Radiokemi; Amyloidos; Pharmaceutical Science; Farmaceutisk vetenskap; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi; Medicinal Chemistry; Läkemedelskemi;

   Sammanfattning : In the first part of this thesis, palladium(0)-catalyzed and -mediated carbonylations are discussed. Paper I describes a new method for the safe, efficient use of a solid carbon monoxide source in the synthesis of primary and secondary benzamides. LÄS MER