Sökning: "neutrophil elastase"

Visar resultat 1 - 5 av 26 avhandlingar innehållade orden neutrophil elastase.

  1. 1. Novel findings on cellular trafficking and targeting for granule storage of neutrophil elastase, a multifunctional effector molecule of innate immunity

    Detta är en avhandling från Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University

    Författare :Linda Källquist; Lund University.; Lunds universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic cell; CD63; neutrophil elastase; targeting; trafficking; intracellular sorting; neutrophil; azurophil granule;

    Sammanfattning : Neutrophil elastase (NE) has important roles in innate immunity, killing pathogens and controlling the immune response; but how NE is targeted to developing granules is not understood. Therefore, the aim of this thesis was to investigate the sorting of NE. LÄS MER

  2. 2. Studies on Cytotoxic and Neutrophil Challenging Polypeptides and Cardiac Glycosides of Plant Origin

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Senia Johansson; Uppsala universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; cytotoxic; neutrophil; polypeptides; Phoradendron tomentosum; Digitalis purpurea; plant; mistletoe; MS MS; Edman degradation; breast cancer; macrocyclic peptides; multidrug resistance protein; primary structures; phoratoxin; isolation; digitoxin; cardiac lycoside; structure-activity; Farmaceutisk kemi; PHARMACY Pharmaceutical chemistry; FARMACI Farmaceutisk kemi; Pharmacognosy; farmakognosi;

    Sammanfattning : This thesis examines the isolation and characterisation (biological and chemical) of polypeptides from plants. A fractionation protocol was developed and applied on 100 plant materials with the aim of isolating highly purified polypeptide fractions from small amounts of plant materials. LÄS MER

  3. 3. Thrombin-induced pulmonary injury in the rat : role of neutrophil elastase and arachidonic acid metabolites

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Chul Min Ahn; Uppsala universitet.; [1996]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 4. Phylogenies and Secondary Chemistry in Arnica (Asteraceae)

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Catarina Ekenäs; Uppsala universitet.; [2008]
    Nyckelord :Biology; phylogeny; ITS; ETS; RPB2; sesquiterpene lactones; PCA; bioassay; NF-κB; neutrophil; chloroplast; Biologi; Arnica; Asteraceae;

    Sammanfattning : The genus Arnica (Asteraceae) was investigated for phylogenetic relationships and sesquiterpene lactone (STL) content with the aims to trace the evolutionary history of the genus and to investigate possible congruencies between DNA sequence data, secondary chemistry, and biological activity. Complex evolutionary patterns in Arnica are evident from phylogenetic analyses of chloroplast regions (the rpl16 and rps16 introns and the psbA–trnH, ycf4–cemA, and trnT–L spacers), nuclear ribosomal regions (the internal and external transcribed spacers) and the nuclear low-copy DNA region coding for the second largest subunit of RNA polymerase II (RPB2) between exons 17 and 23. LÄS MER

  5. 5. Secretory Leukocyte Protease Inhibitor (SLPI) in the gastrointestinal tract in man

    Detta är en avhandling från Max Nyström Dept of Surgical pathophysiology, Malmö university hospital SE 295 02 Malmö Sweden

    Författare :Max Nyström; Lund University.; Lunds universitet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; elastase inhibitors; human leukocyt proteases; Plasma protease inhibitors; NGAL; Ulcerative colitis; Antileukoprotease; IBD; traumatologi; ortopedi; traumatology; orthopaedics; Immunology; serology; transplantation; Immunologi; serologi; Kirurgi;

    Sammanfattning : Secretory leukocyte protease inhibitor is a 11.7 kDa acid stable serine protease inhibitor. SLPI has been shown to be the dominant protease inhibitor in bronchial secretions and has been used in treatment of pulmonary emphysema. LÄS MER