Sökning: "Hypertrophy"

Visar resultat 26 - 30 av 155 avhandlingar innehållade ordet Hypertrophy.

  1. 26. About hyaluronan in the hypertrophic heart : studies on coordinated regulation of extracellular matrix signalling

    Författare :Urban Hellman; Anders Waldenström; Stellan Mörner; Anna Engström-Laurent; Lena Jonasson; Umeå universitet; []
    Nyckelord :hyaluronan; hyaluronan synthases; gene expression; extracellular matrix; cardiac hypertrophy; rat wistar; male ; cardiomyocytes; growth factors; fibroblasts; microvesicles; exosomes; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Background. Myocardial hypertrophy is a risk factor for cardiovascular morbidity and mortality. Independent of underlying disease, the cardiac muscle strives in different ways to compensate for an increased workload. This remodelling of the heart includes changes in the extracellular matrix which will affect systolic and diastolic cardiac function. LÄS MER

  3. 27. Hyaluronan and the receptor CD 44 in the heart and vessels : a study in normal and pathological conditions

    Författare :Martin Hellström; Anna Engström-Laurent; Bengt Johansson; Lena Jonasson; Umeå universitet; []
    Nyckelord :hyaluronan; CD44; heart; Rat; cardiac hypertrophy; artery; vein; human; Medicine; medicin;

    Sammanfattning : Tissues are not solely composed of cells. The extracellular matrix is important for the cell well-being and cell-cell communication. The glycosaminoglycan hyaluronan (HYA) is a widely distributed extracellular matrix (ECM) component. LÄS MER

  4. 28. An epidemiological perspective on heart and lung weight in cardiac and intoxication deaths

    Författare :Torfinn Beer; Carl Johan Wingren; Anders Eriksson; Britt-Marie Stålnacke; Kimberly Molina; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heart weight; lung weight; organ weight; autopsy; forensic pathology; Bayesian analysis; cardiac hypertrophy; fatal intoxication; Forensic Medicine; rättsmedicin;

    Sammanfattning : The main purpose of a medico-legal autopsy is to determine the cause and manner of death. A forensic pathologist makes assessments of this using several sources of information, one of which is the discrepancy between measured organ weight and reference values. LÄS MER

  5. 29. Early parathyroidectomy in mild primary hyperparathyroidism: Effects on heart and bones

    Författare :Erik Almqvist; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; parathyroidectomy; hyperparathyroidism; bone metabolism; testosterone; myocardial hypertrophy; cardiac function; echocardiography; radionuclide angiography; natriuretic peptide; Surgery; orthopaedics; traumatologi; ortopedi; traumatology; Kirurgi;

    Sammanfattning : There is an ongoing controversy regarding how to take care of patients with mild primary hyperparathyroidism (PHPT). Some recommend surgical treatment at diagnosis, others just follow-up as long as there is no evidence of disease progression. LÄS MER

  7. 30. Effects of prenatal IL-6 exposure and hyperinsulinemia on neuroendocrine regulation

    Författare :Anne-Maj Samuelsson; Göteborgs universitet; []
    Nyckelord :interleukin-6; intrauterine exposure; HPA-axis; RAS; hippocampus; spatial learning; hypertension; insulin signaling; cardiac hypertrophy;

    Sammanfattning : Prenatal exposure to infection is associated with several neuroendocrine disorders. We therefore wanted to elucidate if cytokines, generated in response to maternal infection, play a key mechanistic role in this associations. LÄS MER