Sökning: "HPA activity"
Visar resultat 1 - 5 av 37 avhandlingar innehållade orden HPA activity.
1. An Epidemiological Study of Exhaustion in the Context of Chronic stress. Concept, Cortisol, Causes and Consequences
Sammanfattning : The interest in exhaustion has increased rapidly during the last few decades in many developed countries. In Sweden, prevalence of exhaustion increased by 50 percent on average between 1989 and 2005, and recent data reveals that exhaustion still remains at this higher level. Scientifically, exhaustion is not clearly defined. LÄS MER
2. Personality and the HPA-axis in Association with Postpartum Depression
Sammanfattning : Postpartum depression is a psychiatric disorder affecting a substantial proportion of newly delivered women, and remains a significant cause of childbirth-related morbidity. The aim of the present thesis was to examine psychological, endocrine and genetic aspects of postpartum depression in a large, population-based sample of women in Uppsala, Sweden. LÄS MER
3. Studies on the deposition, bioavailability and systemic activity of glucocorticoids in man
Sammanfattning : The local deposition, pharmacokinetics, and systemic activity of inhaled and intranasal glucocorticosteroids in different formulations and devices(ICSs) has been investigated. After nasal administration of the ICS budesonide (Bud), the systemic availability (F) was found to be significantly higher from an aqueous pump spray and from the powder inhaler Turbuhaler, than from a pressurized metered dose inhaler (pMDI), and the uptake process was slower and less complete with the pMDI formulation. LÄS MER
4. Examining Female Resilience to Early Environmental Influences : Short- and long-term consequences on behaviour, HPA axis activity and alcohol intake after prolonged maternal separation
Sammanfattning : Early-life experiences are an important factor influencing further development of the individual. Adverse experiences early in life, such as various kinds of abuse or neglect, are types of early-life stress that can adversely affect an individuals health, as well as contribute to the development of an array of disorders later in life. LÄS MER
5. Hypocortisolism in recurrent affective disorders
Sammanfattning : Bipolar disorders and recurrent depressions are two common psychiatric disorders with a life time prevalence of approximately 1% and 8%, respectively. Despite treatment these patients suffer from affective symptoms up to 50% of the time, resulting in lower well-being. LÄS MER