Sökning: "H Bone"

Visar resultat 1 - 5 av 58 avhandlingar innehållade orden H Bone.

  1. 1. NOTUM and RSPO3 in Bone - WNT signaling modulators regulating the skeleton

    Författare :Karin H. Nilsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NOTUM; RSPO3; WNT signaling; Bone;

    Sammanfattning : Osteoporosis is a skeletal disease affecting millions of people worldwide, often leading to fragility fractures and a decreased quality of life. There is an unmet medical need for new anabolic, bone building, treatments. LÄS MER

  3. 2. Cellular and molecular responses of periodontal connective tissue cells to Actinobacillus actinomycetemcomitans cytolethal distending toxin

    Författare :Georgios N. Belibasakis; Sotirios Kalfas; Ulf H. Lerner; Anders Johansson; Veli-Jukka Uitto; Umeå universitet; []
    Nyckelord :Medical sciences; Actinobacillus actinomycetemcomitans; cytolethal distending toxin; periodontal connective tissue cells; localized aggressive periodontitis; growth arrest; bone resorption; receptor activator of NF-κB ligand; osteoprotegerin; pro-inflammatory cytokines; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; odontologi; Odontology;

    Sammanfattning : Actinobacillus actinomycetemcomitans is present in elevated proportions and numbers in dental bacterial biofilms of patients with localized aggressive periodontitis. This variant of periodontal disease, occurring in adolescents and young adults, is characterized by rapid and severe destruction of the connective tissues and bone supporting the teeth, eventually culminating in tooth loss. LÄS MER

  4. 3. The effect of protein intake and physical exercise on energy turnover and substrate utilisation at energy balance in man

    Författare :Anders H. Forslund; Uppsala universitet; []
    Nyckelord :Medical sciences; Body composition; carbohydrate; energy turnover; fat; protein; stable isotopes; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Nutrition; näringslära;

    Sammanfattning : The principal goal of the thesis has been to evaluate the effect of protein intake and physical exercise on energy turnover and substrate utilisation. Body composition assessment is of importance as an indicator of the energy balance. Therefore, in the first study the aim was to develop new models to estimate body composition more accurately. LÄS MER

  5. 4. Natural killer cell tolerance : influence of the MHC class I expression in the host

    Författare :Maria H Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; MHC class 1; tolerance; transgenic mice; Ly49;

    Sammanfattning : Development of self-tolerance in the immune system is characterized by somatic processes aiming at permanently eliminating, or silencing, potentially autoreactive lymphocytes. Such tolerance mechanisms are of outmost importance if autoimmunity is to be avoided. LÄS MER

  7. 5. In vitro evaluation of hip prostheses

    Författare :H Lucas Anissian; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Aseptic loosening and periprosthetic osteolysis are the most common complications (5-10% in 10 years follow up) after total hip arthroplasty. Polyethylene debris appears to play a major role in this process. LÄS MER