Sökning: "localized aggressive periodontitis"

Hittade 4 avhandlingar innehållade orden localized aggressive periodontitis.

  1. 1. Vesicle-mediated and free soluble delivery of bacterial effector proteins by oral and systemic pathogens

    Författare :Bernard Thay; Jan Oscarsson; Mikael Rhen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periodontitis; Aggregatibacter actinomycetemcomitans; Staphylococcus aureus; membrane vesicles; vesicle-host cell interaction; protein delivery; molekylärbiologi; Molecular Biology;

    Sammanfattning : Periodontitis, the primary cause of tooth-loss worldwide, is a bacterially induced chronic inflammatory disease of the periodontium. It is associated with systemic conditions such as cardiovascular disease (CVD). However, pathogenic mechanisms of periodontitis-associated bacteria that may contribute to the CVD association are unclear. LÄS MER

  3. 2. Cellular and molecular responses of periodontal connective tissue cells to Actinobacillus actinomycetemcomitans cytolethal distending toxin

    Författare :Georgios N. Belibasakis; Sotirios Kalfas; Ulf H. Lerner; Anders Johansson; Veli-Jukka Uitto; Umeå universitet; []
    Nyckelord :Medical sciences; Actinobacillus actinomycetemcomitans; cytolethal distending toxin; periodontal connective tissue cells; localized aggressive periodontitis; growth arrest; bone resorption; receptor activator of NF-κB ligand; osteoprotegerin; pro-inflammatory cytokines; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; odontologi; Odontology;

    Sammanfattning : Actinobacillus actinomycetemcomitans is present in elevated proportions and numbers in dental bacterial biofilms of patients with localized aggressive periodontitis. This variant of periodontal disease, occurring in adolescents and young adults, is characterized by rapid and severe destruction of the connective tissues and bone supporting the teeth, eventually culminating in tooth loss. LÄS MER

  4. 3. Exotoxins of Aggregatibacter actinomycetemcomitans and periodontal attachment loss in adolescents

    Författare :Carola Höglund Åberg; Anders Johansson; Rolf Claesson; Dorte Haubek; Andrea Mombelli; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aggregatibacter actinomycetemcomitans; periodontal attachment loss; JP2 genotype; non-JP2 genotype; LtxA; Cdt; Infectious Diseases; infektionssjukdomar;

    Sammanfattning : Aggregatibacter actinomycetemcomitans is an oral bacterium that is mainly associated with aggressive forms of periodontitis, which most often starts at an early age. Amongst the virulence factors of A. LÄS MER

  5. 4. Outer membrane vesicle-mediated export of virulence factors from Gram-negative bacteria

    Författare :Pramod Kumar Rompikuntal; Sun Nyunt Wai; Ann-Beth Jonsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Outer membrane vesicles; CDT; PGN; PrtV; Campylobacter jejuni; Vibrio cholerae; Aggregatibacter actinomycetemcomitans; molekylärbiologi; Molecular Biology;

    Sammanfattning : The Gram-negative, motile bacterium Campylobacter jejuni is a causative agent of food-borne gastroenteritis. Cytolethal distending toxin (CDT) is one of the important virulence factors for C. jejuni pathogenesis. It was not previously known how CDT is released from C. LÄS MER