Sökning: "Genomics of sex"
Visar resultat 1 - 5 av 19 avhandlingar innehållade orden Genomics of sex.
1. Complex disease genetics : Utilising targeted sequencing and homogeneous ancestry
Sammanfattning : The complex disease investigations presented in this thesis aimed to provide new information regarding underlying genetics by using targeted sequencing and ethnically homogeneous cohorts. This work moved past current methodologies and addressed data stratification issues, that might have been hindering new findings. LÄS MER
2. Evolution of sex chromosomes in Sylvioidea songbirds
Sammanfattning : Sex chromosomes were discovered more than 100 years ago. They have been studied intensely from a theoretical perspective since then, giving rise to a large body of testable predictions about their evolution from autosomes. LÄS MER
3. Ancient genomics of Baltic seals : Insights on the past Baltic grey seal and harp seal populations
Sammanfattning : This thesis aims to study and describe the ancient populations of grey and harp seals in the Baltic Sea, and to present new methodological approaches for general use in ancient DNA studies.The dissertation is comprised of five studies: a review of the use of paleogenetics in studying ancient human-marine mammal interactions; a method paper investigating patterns of DNA preservation in ancient pinniped samples; a method paper presenting a genetic sex identification method for ancient pinnipeds; a population genomic study of the Baltic grey seal; and a population genomic study of the now extinct Baltic harp seal. LÄS MER
4. Splitting the sexes : The birth and senescence of sex chromosomes
Sammanfattning : The evolution of gonochorism from hermaphroditism can be gradual by increasing investment in one sex role while decreasing in the other, or rapid through the fixation of sex-role sterility mutations, eventually leading to the evolution of sex chromosomes. It is expected that the transition will involve a temporary state of gynodioecy or androdioecy as the mutations are not expected to take place at the same time. LÄS MER
5. Speciation genomics in Ficedula flycatchers
Sammanfattning : Understanding what evolutionary processes have shaped patterns of genomic differentiation between species is a major aim of speciation genomics. However, disentangling the role of different processes that generate similar patterns remains a substantial challenge. LÄS MER