Sökning: "Dyskinesia"

Visar resultat 1 - 5 av 48 avhandlingar innehållade ordet Dyskinesia.

  1. 1. Transcriptional dysregulation in L-DOPA-induced dyskinesia

    Detta är en avhandling från Angela Cenci Nilsson,Wallenberg Neuroscience Centre, Neurobiology Division, BMC A11, 221 84 Lund

    Författare :Malin Andersson; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; neurofysiologi; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; CREB; jun; fos; immediate early genes; prodynorphin; striatal plasticity; Parkinson s disease; dyskinesia; Klinisk genetik;

    Sammanfattning : This study explores the role of transcriptional regulation important in the development of L-DOPA-induced dyskinesia in a rat model of Parkinson’s disease. In patients with Parkinson’s disease, dyskinesia is one of the most difficult complications of the DA-replacement therapy by L-DOPA. LÄS MER

  2. 2. Presynaptic mechanisms in L-DOPA-induced dyskinesia

    Detta är en avhandling från Department of Experimental Medical Science, Lund Univeristy

    Författare :Hanna Lindgren; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; dyskinesia; 5-HT; DA; Parkinson s disease; 6-OHDA; microdialysis;

    Sammanfattning : This study has investigated the impact of presynaptic factors on the development of dyskinesia during chronic L-DOPA treatment in a rat model of Parkinson’s disease (PD). The mechanisms causing dyskinesia are not completely understood but have been proposed to involve changes in gene and protein expression in striatal neurons, which are the main target of dopamine (DA) projections from the substantia nigra pars compacta (SNpc). LÄS MER

  3. 3. Modelling parkinsonian akinesia and dyskinesia in dopamine depleted rodents

    Detta är en avhandling från Martin Lundblad, Basal Ganglia, Lund University

    Författare :Martin Lundblad; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; Neurology; mouse; rat; 6-OHDA; dyskinesia; Parkinson s disease; L-DOPA;

    Sammanfattning : Animal models of Parkinson’s disease and L-DOPA-induced dyskinesia are essential to explore pathophysiological hypotheses and to test new treatment options. There are many different animal models of Parkinson's disease, which differ greatly with respect to species, mechanisms of nigral cell death, and extent of dopamine-dependent motor deficits. LÄS MER

  4. 4. Studies in tardive dyskinesia

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ulf Andersson; Uppsala universitet.; [1988]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 5. Neuroleptic-induced persistent dyskinesia : behavioural and biochemical studies

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jan-Erik Häggström; Uppsala universitet.; [1984]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER