Sökning: "Motor fluctuations"

Visar resultat 1 - 5 av 26 avhandlingar innehållade orden Motor fluctuations.

1. 1. Stochastic modeling of motor proteins

   Författare :Martin Lindén; Mats Wallin; Dean Astumian; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molecular motor; motor protein; Markov process; fluctuations; statistical mechanics; microscopic reversibility; Physics; Fysik;

   Sammanfattning : Motor proteins are microscopic biological machines that convert chemical energy into mechanical motion and work. They power a diverse range of biological processes, for example the swimming and crawling motion of bacteria, intracellular transport, and muscle contraction. LÄS MER

3. 2. Parkinson's Disease with Device, Diary, or in Disguise. Dyskinesia reduction, motor state evaluation, and workforce participation among persons with Parkinson's disease

   Författare :Jonathan Timpka; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; Parkinson disease; Levodopa infusion; Motor fluctuations; Dyskinesia; Workforce participation; Work ability; Sickness absence; Employment; Patient reported outcome;

   Sammanfattning : INTRODUCTION: In the wait for disease-modifying treatment for Parkinson’s disease (PD), efforts towards improved symptom control and reduced negative effects of PD can result in meaningful change patients. The general efficacy of levodopa-carbidopa intestinal gel (LCIG) in advanced PD has been established, but its effects on dyskinesia need more investigation. LÄS MER

4. 3. Cell and Gene Therapy for Parkinson's Disease: Therapeutic Effect and Modulation of Dyskinesias in the 6-OHDA Rat Model

   Författare :Thomas Carlsson; Brain Repair and Imaging in Neural Systems (BRAINS); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Pharmacological sciences; pharmacognosy; pharmacy; neurofysiologi; Medicin människa och djur ; Neurology; neuropsychology; neurophysiology; Neurologi; Medicine human and vertebrates ; Parkinson?s disease; Serotonin; Tyrosine hydroxylase; Ventral mesenchephalon; Motor behavior; L-DOPA; GTP cyclohydrolase 1; Gene therapy; Dyskinesias; Cell transplantation; Dopamine; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

   Sammanfattning : The main pathological feature in Parkinson's disease is the progressive loss of dopamine neurons in the midbrain, which in turn leads to the appearance of motor deficits such as akinesia/bradykinesia (loss/slowness of movements), rigidity, postural imbalance and tremor. To this day, there is no cure for the disease, but there are medications to relieve the symptoms. LÄS MER

5. 4. First-principle data-driven models for assessment of motor disorders in Parkinson’s disease

   Författare :Taha Khan; Peter Funk; Mark Dougherty; Jerker Westin; Shahina Begum; Gunnar Klein; Mälardalens högskola; []
   Nyckelord :Computer Science; datavetenskap; Complex Systems – Microdata Analysis;

   Sammanfattning : Parkinson’s disease (PD) is an increasing neurological disorder in an aging society. The motor and non-motor symptoms of PD advance with the disease progression and occur in varying frequency and duration. In order to affirm the full extent of a patient’s condition, repeated assessments are necessary to adjust medical prescription. LÄS MER

7. 5. Insurance and cartels through wars and depressions : Swedish Marine insurance and reinsurance between the World Wars

   Författare :Gustav Jakob Petersson; Magnus Lindmark; Lars-Fredrik Andersson; Robin Pearson; Umeå universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Interwar period; world war I; first world war; second world war; world war II; deflation crisis; great depression; insurance history; marine insurance; Swedish insurance; international insurance; cartel theory; reinsurance theory; risk diversification theory; agency theory; exchange-rate fluctuations; currency risks; monetary risks; British competition; English competition; Lloyd s; cartelisation; cartel; international cartel; tariffs; stock insurance company; mutual insurance company; stock insurers; mutual insurers; The Swedish Association of Marine Underwriters; Sjöassuradörernas förening; prohibition of competition; price agreements; market division agreements; cheating; international competition; The International Union of Marine Insurance; IUMI; Internationaler Transport-Versicherungs-Verband; reinsurance; reinsurance retention ratio; loss ratio; combined ratio; reinsurance crisis; information asymmetry; information asymmetries; risk diversification; Internationaler Transport-Versicherungs-Verband; Versicherungsgeschichte; Transportversicherung; Zwischenkriegszeit; Versicherungskrise; Versicherungskartell; Rückversicherung; Mellankrigstiden; första världskriget; andra världskriget; deflationskrisen; stora depressionen; försäkringshistoria; marinförsäkring; sjöförsäkring; svensk försäkring; internationell försäkring; kartellteori; återförsäkringsteori; riskdiversifiering; incitamentsteori; växelkursfluktuationer; valutarisk; brittisk konkurrens; engelsk konkurrens; Lloyd s; monetär risk; kartellisering; tariffer; försäkringsaktiebolag; ömsesidiga försäkringsbolag; Sjöassuradörernas förening; The Swedish Association of Marine Underwriters; prisöverenskommelser; marknadsuppdelningsavtal; konkurrensförbud; konkurrensavtal; avtalsbrott; internationell konkurrens; The International Union of Marine Insurance; IUMI; Internationaler Transport-Versicherungs-Verband; återförsäkring; återförsäkringskris; återförsäkringsgrad; informationsassymetrier; riskdiversifiering; förlustkvot; ekonomisk historia; Economic History;

   Sammanfattning : The aim of this thesis is to enhance our understanding of Swedish marine insurers' choices of business strategies under the potentially difficult business circumstances of the interwar period 1918-1939. Little previous research exists on marine insurance during the interwar period. LÄS MER