Sökning: "Domain Evolution"

Visar resultat 31 - 35 av 192 avhandlingar innehållade orden Domain Evolution.

  1. 31. Design Methods and Processes for ML/DL models

    Författare :Meenu Mary John; Helena Holmström Olsson; Jan Bosch; Maria Paasivaara; Malmö universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Machine Learning; Deep Learning; Development; Deployment; Evolution;

    Sammanfattning : Context: With the advent of Machine Learning (ML) and especially Deep Learning (DL) technology, companies are increasingly using Artificial Intelligence (AI) in systems, along with electronics and software. Nevertheless, the end-to-end process of developing, deploying and evolving ML and DL models in companies brings some challenges related to the design and scaling of these models. LÄS MER

  3. 32. Evolutionary and functional studies of protein H: a surface molecule of Streptococcus pyogenes

    Författare :Inga-Maria Frick; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracellular transportation; adhesion; aggregation; FNIII domain; albumin-binding; M-like protein; convergent evolution; protein G; Streptococcus pyogenes; IgG-binding; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Several bacterial species express surface proteins with affinity for the Fc part of human IgG. This thesis describes evolutionary and functional studies of protein H, an IgGFc-binding surface protein of the human pathogen Streptococcus pyogenes. LÄS MER

  4. 33. The deep evolutionary roots of non-coding RNA - a comparative genomics approach

    Författare :Marc Patrick Hoeppner; Anthony M. Poole; Britt-Marie Sjöberg; Jürgen Brosius; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-coding RNA; evolution; comparative genomics; RNA world; introns; snoRNA; miRNA; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : Non-coding RNAs (ncRNA) are a diverse group of genes that do not encode proteins but function exclusively on the level of RNA and were originally suggested to be remnants of a pre-DNA stage of life known as the RNA world. More recent work, however, has uncovered a rich repertoire of previously unknown families with possible consequences for our understanding of the origin and evolution of the modern RNA infrastructure. LÄS MER

  5. 34. The rise and fall of IgE

    Författare :Molly Vernersson; Rikard Holmdahl; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Immunoglobulin; IgE; evolution; atopic allergy; vaccine; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molecular Immunology; molekylär immunologi;

    Sammanfattning : Immunoglobulin E (IgE) occurs exclusively in mammals and is one of five immunoglobulin (Ig) classes found in man. Unlike other isotypes, IgE is best known for its pathological effects, whereas its physiological role remains somewhat elusive. LÄS MER

  7. 35. NMR Studies of Bacterial Albumin-Binding Modules

    Författare :Maria U Johansson; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fysikalisk kemi; Biotechnology; Bioteknik; Proteins; enzymology; Proteiner; enzymologi; Physical chemistry; three-helix bundle; protein structure; protein PAB; protein-protein interactions; protein G; protein dynamics; NMR; module shuffling; GA module; evolution; albumin-binding; bacterial surface proteins;

    Sammanfattning : Peptostreptococcus magnus and group C/G streptococci are Gram-positive cocci that are part of the normal flora and reside in more or less the same locations in the host. Protein G of group C/G streptococci was originally described as binding IgGFc of several species and later shown to also bind human serum albumin and albumins from various animal species. LÄS MER