Sökning: "DQB1"

Visar resultat 21 - 25 av 35 avhandlingar innehållade ordet DQB1.

  1. 21. Contribution of Immunogenetic Factors in Susceptibility to Cervical Cancer

    Författare :Emma Ivansson; Ulf Gyllensten; Patrik Magnusson; Allan Hildesheim; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical genetics; Medicinsk genetik;

    Sammanfattning : Cervical cancer is the second most common cancer in women worldwide. Persistent infection by an oncogenic type of human papillomavirus (HPV) is a necessary but not sufficient cause and there is also a genetic component. LÄS MER

  3. 22. Human Papillomavirus Load and Cervical Carcinoma

    Författare :Martin Moberg; Ulf Gyllensten; Björn Hagmar; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; cervical cancer; human papillomavirus; viral load; HLA class II; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Sammanfattning : Human Papillomavirus (HPV) is a key factor in the development of cervical cancer. Out of the more than 100 known HPV types 13 are considered oncogenic. In addition to presence of the virus several other factors have been proposed to influence risk of cervical cancer. LÄS MER

  4. 23. Consequences of multiple sclerosis for patients in Sweden

    Författare :Sarah Burkill; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This study aimed to consider consequences of multiple sclerosis for patients in Sweden throughout various stages of the life course. The thesis was separated into four constituent papers, which dealt with different aspects of the disease, its symptoms, and implications at different life stages. LÄS MER

  5. 24. Human leukocyte antigens with special reference to association and linkage in multiple sclerosis

    Författare :Anna Fogdell-Hahn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HLA; MHC; multiple sclerosis; narcolepsy; lod score; linkage.;

    Sammanfattning : The polymorphism of HLA (human leukocyte antigen) is extensive. Allelic variation has previously been detected by cellular and serological methods. Today a variety of genomic typing techniques have been developed, which give higher resolution and a possibility to detect single nucleotide variations. LÄS MER

  7. 25. Searching for Celiac Disease Screening-detected celiac disease in an HLA-genotyped birth cohort

    Författare :Sara Björck; Celiaki och diabetes; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone mineral density; inflammation; cytokine; screening; HLA; tissue transglutaminase antibody; children; Celiac disease; vitamin D; parathyroid hormone;

    Sammanfattning : Objectives: Celiac disease is a common immune mediated enteropathy strongly associated with HLA-DQB1*02 (DQ2), *0302 (DQ8), or both and the presence of tissue transglutaminase autoantibodies (tTGA). Prevalence studies have revealed that most affected individuals go undetected because of subclinical signs or being asymptomatic rendering screening a method for identification. LÄS MER