Sökning: "narcolepsy"
Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet narcolepsy.
1. Narcolepsy in children: Relationship to the H1N1 influenza vaccination, association with psychiatric and cognitive impairments and consequences in daily life
Sammanfattning : Background/aims: Narcolepsy is a lifelong sleep disorder with an onset most frequently in the second decade of life. The cardinal symptoms are excessive daytime sleepiness, cataplexy, hypnagogic and hypnopompic hallucinations sleep paralysis and disturbed nighttime sleep. LÄS MER
2. Brain Networks and Dynamics in Narcolepsy
Sammanfattning : Narcolepsy is a chronic sleep disorder, characterised by excessive daytime sleepiness with frequent uncontrollable sleep attacks. In addition to sleeprelated problems, changes in cognition have also been observed in patients with narcolepsy and has been linked to the loss of Orexin-A in a number of studies. LÄS MER
3. Autoimmunogenetic Aspects of Vaccine-induced Narcolepsy. As part of the AMINA - Autoimmune Multiple Sclerosis and Narcolepsy Study
Sammanfattning : Narcolepsy type 1 (NT1) is a neurological sleep disorder. The biological cause is the degeneration of hypocretin neurons located in the hypothalamus. It has been suggested that NT1 has an autoimmune pathogenesis, as in most patients, the Human Leukocyte Antigen (HLA)-DQB1*06:02:01 is present. LÄS MER
4. Human leukocyte antigens with special reference to association and linkage in multiple sclerosis
Sammanfattning : The polymorphism of HLA (human leukocyte antigen) is extensive. Allelic variation has previously been detected by cellular and serological methods. Today a variety of genomic typing techniques have been developed, which give higher resolution and a possibility to detect single nucleotide variations. LÄS MER
5. Vaccine safety, vaccine effectiveness and other determinants for successful immunisation programmes
Sammanfattning : The studies in this thesis examined several key determinants for successful uptake of vaccinations in the Nordic countries, with focus on vaccine safety and vaccine effectiveness. In study I, we investigated whether disease history is a risk factor for narcolepsy after vaccination with the pandemic influenza vaccine, Pandemrix, which was circulated between 2009 and 2010. LÄS MER