Sökning: "Björn Hagmar"

Hittade 2 avhandlingar innehållade orden Björn Hagmar.

1. 1. Molecular Pathogenesis of Cervical Carcinoma : Analysis of Clonality, HPV16 Sequence Variations and Loss of Heterozygosity

   Författare :Xinrong Hu; Björn Hagmar; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical carcinoma; CIN; HPV; LOH; X-chromosome inactivation; clonality; molecular pathogenesis; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : A previous model of morphological pathogenesis assumed that cervical carcinoma is of monoclonal origin and progresses through multiple steps from normal epithelium via CINS into invasive carcinomas. The aim of this study was to investigate the molecular mechanism of pathogenesis of cervical neoplasia. LÄS MER

3. 2. Human Papillomavirus Load and Cervical Carcinoma

   Författare :Martin Moberg; Ulf Gyllensten; Björn Hagmar; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; cervical cancer; human papillomavirus; viral load; HLA class II; Molekylärbiologi; Molecular biology; Molekylärbiologi;

   Sammanfattning : Human Papillomavirus (HPV) is a key factor in the development of cervical cancer. Out of the more than 100 known HPV types 13 are considered oncogenic. In addition to presence of the virus several other factors have been proposed to influence risk of cervical cancer. LÄS MER