Sökning: "tissue transglutaminase antibody"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden tissue transglutaminase antibody.

1. 1. Serologic Markers in Screening for Coeliac Disease, Clinical significance and immunogenetic basis

   Författare :Klas Sjöberg; Gastroenterologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastro-enterology; transglutaminase; specificity; sensitivity; prevalence; HLA; liver disease; endomysial antibodies; gliadin antibodies; diabetes; Autoimmune disease; coeliac disease; Gastroenterologi;

   Sammanfattning : The prevalence of coeliac disease (CD) was initially estimated to 1/1537. Based on serial analysis [GA and endomysial antibodies (EMA)], the prevalence was 6/1970 (0.30%). In autoimmune chronic hepatitis 5. LÄS MER

3. 2. Coeliac disease : Clinical and immunological aspects

   Författare :Tony Hansson; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Coeliac disease; cytokines; TGF-beta; tissue transglutaminase; IL-4; IFN-gamma; TNF-alpha; ELISPOT; anti-endomysiumantibodies; anti-gliadin antibodies; Onkologi; Oncology; Onkologi; Klinisk immunologi; Clinical Immunology;

   Sammanfattning : A better immunological definition of coeliac disease and highly discriminatory serum markers are needed to identify children with early mucosal lesions and for rapid follow-up and a better knowledge of antigen reactivity and cytokine production will be needed to clarify the pathogenic mechanisms.The numbers of circulating IgAanti-gliadin antibody-producing (IgAAGA SFC) cells were increased in patients with untreated coeliac disease compared to controls and treated coeliac disease patients. LÄS MER

4. 3. Searching for Celiac Disease Screening-detected celiac disease in an HLA-genotyped birth cohort

   Författare :Sara Björck; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone mineral density; inflammation; cytokine; screening; HLA; tissue transglutaminase antibody; children; Celiac disease; vitamin D; parathyroid hormone;

   Sammanfattning : Objectives: Celiac disease is a common immune mediated enteropathy strongly associated with HLA-DQB1*02 (DQ2), *0302 (DQ8), or both and the presence of tissue transglutaminase autoantibodies (tTGA). Prevalence studies have revealed that most affected individuals go undetected because of subclinical signs or being asymptomatic rendering screening a method for identification. LÄS MER

5. 4. The Perfect Storm? Gluten and type 1 diabetes

   Författare :Emma Adlercreutz; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NKG2D; Celiac disease autoimmunity; Gluten; Type 1 diabetes; Perinatal risk;

   Sammanfattning : Aim: The general objective of the present research was to study the association between type 1 diabetes and celiac disease, and the effects of dietary gluten on the risk of developing type 1 diabetes. More specific aims were as follows: to estimate the prevalence of celiac-disease-associated autoantibodies in children with type 1 diabetes; to study the connection between non-HLA genetic risk markers and autoantibodies associated with type 1 diabetes and celiac disease during the first year after diagnosis of type 1 diabetes; to investigate the effect of gluten on the risk of developing type 1 diabetes; to evaluate the impact of perinatal factors on the risk of developing both type 1 diabetes and celiac disease. LÄS MER

7. 5. Biomarkers of Inflammation and Intestinal Mucosa Pathology in Celiac Disease

   Författare :Hanna Gustafsson Bragde; Jan Söderman; Ulf Jansson; Ewa Grodzinsky; Mats Fredrikson; Ross McManus; Linköpings universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Celiac disease (CD) is a chronic small intestinal immune-mediated enteropathy triggered by gluten. The only currently available treatment is complying with a lifelong gluten-free diet, which should not be commenced before a CD diagnosis has been established by diagnostic test results (including histopathologic assessment of small intestinal biopsies and CD-specific antibody levels). LÄS MER