Sökning: "DOSE index"

Visar resultat 1 - 5 av 130 avhandlingar innehållade orden DOSE index.

  1. 1. Quality of life, mortality and exacerbations in COPD

    Författare :Josefin Sundh; Scott Montgomery; Christer Janson; Björn Ställberg; Anne Lindberg; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; HRQL; CCQ; comorbidity; mortality; DOSE index; SMR; exacerbations; asthma COPD clinic; Medicine; Medicin;

    Sammanfattning : Background: Risk factors for poor health related quality of life (HRQL), mortality and exacerbations in Chronic Obstructive Pulmonary Disease (COPD) need to be explored.Objectives: To examine associations of comorbidity and Body Mass Index (BMI) with HRQL using the Clinical COPD Questionnaire (CCQ); to examine the prognostic qualities of the multidimensional instrument DOSE index; to examine the association of health status estimated by the CCQ with mortality; and to examine management of exacerbations and subsequent exacerbation risk. LÄS MER

  3. 2. Mathematical Modelling of Dose Planning in High Dose-Rate Brachytherapy

    Författare :Björn Morén; Torbjörn Larsson; Åsa Carlsson Tedgren; Sebastiaan Breedveld; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Cancer is a widespread type of diseases that each year affects millions of people. It is mainly treated by chemotherapy, surgery or radiation therapy, or a combination of them. One modality of radiation therapy is high dose-rate brachytherapy, used in treatment of for example prostate cancer and gynecologic cancer. LÄS MER

  4. 3. Developing and evaluating dose calculation models for verification of advanced radiotherapy

    Författare :Jörgen Olofsson; Mikael Karlsson; Anders Ahnesjö; Crister Ceberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation therapy; high-energy photons; dose calculation; multi-source model; pencil kernel; uncertainties; action levels; Radiological physics; Radiofysik;

    Sammanfattning : A prerequisite for modern radiotherapy is the ability to accurately determine the absorbed dose (D) that is given to the patient. The subject of this thesis has been to develop and evaluate efficient dose calculation models for high-energy photon beams delivered by linear accelerators. LÄS MER

  5. 4. Cone Beam Computed Tomography - radiation dose and image quality assessments

    Författare :Sara Lofthag-Hansen; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cone beam computed tomography; anatomic landmarks; dose-area product; image quality; implant planning; periapical diagnosis; radiation dosimetry;

    Sammanfattning : Diagnostic radiology has undergone profound changes in the last 30 years. New technologies are available to the dental field, cone beam computed tomography (CBCT) as one of the most important. LÄS MER

  7. 5. Optimal design for dose-finding studies

    Författare :Renata Eirini Tsirpitzi; Frank Miller; Kirsten Schorning; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bivariate model; distortion; drug combination; Elfving set; Emax model; Fedorov algorithm; mixed effects models; optimal experimental design; Statistics; statistik;

    Sammanfattning : One of the most complex tasks during the clinical development of a new drug is to find a correct dose. Optimal experimental design has as a goal to find the best ways to perform an experiment considering the available resources and the statistical model. Optimal designs have already been used to determine the design of dose-finding studies. LÄS MER