Sökning: "Comparison of in vitro"

Visar resultat 1 - 5 av 195 avhandlingar innehållade orden Comparison of in vitro.

  1. 1. On magnesium-modified titanium coatings and magnesium alloys for oral orthopaedic applications : in vitro investigation

    Författare :Francesca Cecchinato; Malmö högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biocompatible material; Bone substitutes; Biomaterial; Dentala implantat;

    Sammanfattning : In dentistry and orthopaedic surgery, research to find and developimproved biomaterials is progressing rapidly.Of specific interest is to accelerate bone formation around theimplant surface, which could improve the reliability of the implanteven in patients with compromised situations. LÄS MER

  2. 2. Pluripotent Stem Cells of Embryonic Origin : Applications in Developmental Toxicology

    Författare :Måns Jergil; Lennart Dencker; Aldert Piersma; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Embryonic stem cell; Microarray; Toxicogenomics; Valproic acid; Developmental toxicology; Teratogenicity; Neural tube defects; Histone deacetylase inhibitor; In vitro toxicology; Toxicology; Toxikologi; Toxicology; Toxikologi;

    Sammanfattning : General toxicity evaluation and risk assessment for human exposure is essential when developing new pharmaceuticals and chemicals. Developmental toxicology is an important part of this risk assessment which consumes large resources and many laboratory animals. LÄS MER

  3. 3. Acute Lymphoblastic Leukaemia in Adult Patients : Studies of Prognostic Factors, Treatment Results and in vitro Cellular Drug Resistance

    Författare :Helene Hallböök; Bengt Smedmyr; Elin Lindhagen; Lorentz Brinch; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; acute lymphoblastic leukaemia; adult; adolescent; chemotherapy; stem cell transplantation; in vitro assay; imatinib; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Treatment results and clinical characteristics in adult acute lymphoblastic leukaemia (ALL) were evaluated regarding three issues: a new treatment with cytarabine up-front, stem cell transplantation and a comparison between adult and paediatric treatment protocols. All studies were conducted on a national basis. LÄS MER

  4. 4. In vitro Bioaccessibility of Carotenes: Influence of microstructure in tomato and carrot as modified by processing

    Författare :Cecilia Svelander; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; α-carotene; in vitro bioaccessibility; high-pressure homogenisation; carrot; in vivo bioavailability; Caco-2 cell model; blanching; processing; Lycopene; β-carotene; tomato; microstructure;

    Sammanfattning : Carotenes are a group of fat-soluble pigments in many fruits and vegetables associated with several important biological effects, like protection against the development of some forms of cancer and cardiovascular disease. The carotene bioavailability in plant foods, i.e. LÄS MER

  5. 5. Towards High-Throughput Phenotypic and Systemic Profiling of in vitro Growing Cell Populations using Label-Free Microscopy and Spectroscopy : Applications in Cancer Pharmacology

    Författare :Obaid Aftab; Mats Gustafsson; Neil Carragher; Uppsala universitet; []
    Nyckelord :label free vesicle detector; high-throughput; phase contrast microscopy; Library of Pharmacologically Active Compounds; High Content Screening; fluorometric microculture cytotoxicity assay; nuclear magnetic resonance; mass spectrometry;

    Sammanfattning : Modern techniques like automated microscopy and spectroscopy now make it possible to study quantitatively, across multiple phenotypic and molecular parameters, how cell populations are affected by different treatments and/or environmental disturbances. As the technology development at the instrument level often is ahead of the data analytical tools and the scientific questions, there is a large and growing need for computational algorithms enabling desired data analysis. LÄS MER