Sökning: "fluorometric microculture cytotoxicity assay"
Visar resultat 1 - 5 av 14 avhandlingar innehållade orden fluorometric microculture cytotoxicity assay.
1. Chemotherapy in Childhood Acute Lymphoblastic Leukemia : In vitro cellular drug resistance and pharmacokinetics
Sammanfattning : The aims of the studies described in this thesis were to investigate the pharmacokinetics of and cellular resistance to chemotherapy as causes of treatment failure in childhood acute lymphoblastic leukemia (ALL).Leukemic cells from 370 children with newly diagnosed ALL were tested by the Fluorometric Microculture Cytotoxicity Assay to measure their resistance to each of ten standard cytotoxic drugs. LÄS MER
2. Application of In Vitro Chemosensitivity Testing for Evaluation of New Cytotoxic Drugs in Chronic Lymphocytic Leukaemia
Sammanfattning : Despite major advances in the understanding of the biology of chronic lymphocytic leukaemia (CLL), progress in improving its treatment has been limited and it still remains an incurable disorder. In the present research, we have performed in vitro drug sensitivity testing of primary CLL cells for preclinical evaluation of cytotoxic drugs, using the fluorometric microculture cytotoxicity assay (FMCA). LÄS MER
3. The fluorometric microculture cytotoxicity assay (FMCA) in assessment of the clinical activity of cytotoxic drugs : with special reference to ovarian carcinoma
Sammanfattning : .... LÄS MER
4. Feasibility of the fluorometric microculture cytotoxicity assay (FMCA) in the preclinical evaluation of anticancer drugs
Sammanfattning : .... LÄS MER
5. In vitro analysis of cytotoxic drug activity in acute leukemia using the fluorometric microculture cytotoxicity assay (FMCA)
Sammanfattning : .... LÄS MER