Sökning: "Caroline Haglund"

Hittade 4 avhandlingar innehållade orden Caroline Haglund.

  1. 1. Integrating Efficacy and Toxicity in Preclinical Anticancer Drug Development : Methods and Applications

    Författare :Caroline Haglund; Elin Lindhagen; Rolf Larsson; Anna Åleskog; Sigurd Vitols; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticancer drugs; In vitro assays; Toxicity testing; Haematological toxicity; Primary tumour cells; Species difference; Clinical pharmacology; Klinisk farmakologi; Clinical Pharmacology; Klinisk farmakologi;

    Sammanfattning : Preclinical testing is an important part of cancer drug development. The aim of this thesis was to establish and evaluate preclinical in vitro methods useful in the development of new anticancer drugs. In paper I, the development of non-clonogenic assays (FMCA-GM) using CD34+ stem cells for assessment of haematological toxicity was described. LÄS MER

  2. 2. Laminar-flow Liquid-to-air Heat Exchangers - Energy-efficient Display Cabinet Applications

    Författare :Caroline Haglund Stignor; Värmeöverföring; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; energy-efficiency; indirect cooling; display cabinet; pressure drop; heat transfer; flat-tube heat exchanger; cooling coil; laminar;

    Sammanfattning : Provisions are stored and displayed in supermarkets and grocery stores, at a temperature lower than the ambient, in display cabinets, which are responsible for a significant amount of the energy use in this sector. During the 1990s, major changes in the regulations governing the use of synthetic refrigerants took place in Sweden. LÄS MER

  3. 3. Organophosphates and phthalates in air and dust from indoor environments : Method development and applied measurements

    Författare :Caroline Bergh; Conny Östman; Peter Haglund; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Organophosphate esters; phthalate esters; air; dust; sampling; method development; GC MS; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Organophosphate and phthalate esters are polymer additives that are frequently found in air and dust in indoor environments. This thesis describes the development and application of air sampling and selective mass spectrometric (MS) determination of these two compound groups. LÄS MER

  4. 4. Analytical methods for biomolecules involved in atmospheric aerosol formation in the Arctic

    Författare :Farshid Mashayekhy Rad; Ulrika Nilsson; Caroline Leck; Leopold Ilag; Peter Haglund; Stockholms universitet; []

    Sammanfattning : In the Arctic, increasing ice-free conditions and nutrients freed from the melting ice must strongly influence the marine life. Aerosol emissions from microbiological marine processes may affect the low clouds and fogs over the summer Arctic, which in turn have effects on the melting of sea ice. LÄS MER