Sökning: "Ca2 oscillation"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Ca2 oscillation.
Sammanfattning : Signal transduction via ion fluxes is of vital importance for all mammalian cells. Cells can exploit ion regulatory mechanisms to generate and transmit intracellular signals. Improvements in digital microscopic imaging technology have made it possible to explore microenvironments and complex intracellular machineries. LÄS MER
2. Dopaminergic and serotonergic modulation of cellular and locomotor network properties in the lamprey spinal cord
Sammanfattning : Motor activity is the basis for all behavior. It is therefore important to study the processes generating movement such as the neuronal networks in the spinal cord that generates and controls locomotion. The lamprey is used as a model system for the study of locomotion. Although, the lamprey is a simple vertebrate. LÄS MER
Sammanfattning : Calcium (Ca2+) is a highly versatile ion used for intra- and inter-cellular signalling in eukaryotic cells, and numerous cellular events are regulated by alteration of the intracellular Ca2+ concentration. We hypothesized that bacterial virulence factors may alter the Ca 2+ homeostasis in epithelial cells such that the innate immune response is affected. LÄS MER
4. Cellular mechanisms of interaction between uropathogenic Escherichia coli and renal epithelial cells
Sammanfattning : Urinary tract infections will often, particularly in children, lead to renal scar formation or hypoplastic small kidneys post-infectiously. The most common causative agent is uropathogenic Escherichia coli (E. coli). LÄS MER
Sammanfattning : Diminished insulin secretion and dysregulated glucagon secretion are key features of type 2 diabetes (T2D). The overall aim of this thesis was to study the role of cocaine- and amphetamine-regulated transcript (CART) in islet cell function and how CART regulates glucose homeostasis. LÄS MER