Sökning: "Calcium-dependent potassium channels"

Hittade 4 avhandlingar innehållade orden Calcium-dependent potassium channels.

  1. 1. Ion channels and intrinsic membrane properties of locomotor network neurons in the lamprey spinal cord

    Författare :Di Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ion channels; calcium activated non-selective cation current ICAN ; L-type LVA calcium channels Cav 1.3 ; calcium channels; calcium imaging; NMDA; postinhibitory rebound PIR ; lamprey; central pattern generator CPG ; locomotion;

    Sammanfattning : NMDA-receptor dependent membrane potential oscillations and postinhibitory rebound are examples of intrinsic membrane properties of many neurons of rhythm-generating networks, and are considered to play major roles in the operation of the spinal locomotor network of the lamprey vertebrate model. A significant feature of many lamprey spinal cord neurons is their ability to generate pacemaker-like membrane potential oscillations in the presence of the glutamate agonist NMDA. LÄS MER

  3. 2. Dopaminergic and serotonergic modulation of cellular and locomotor network properties in the lamprey spinal cord

    Författare :Martin Wikström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :5-hydroxytryptamine; Dopamine; Calcium channels; Calcium-dependent potassium channels; Afterhyperpolarization; Membrane potential oscillation; Synaptic transmission; Modulation; Central pattern generator; Locomotion; Spinal cord; Lamprey;

    Sammanfattning : Motor activity is the basis for all behavior. It is therefore important to study the processes generating movement such as the neuronal networks in the spinal cord that generates and controls locomotion. The lamprey is used as a model system for the study of locomotion. LÄS MER

  4. 3. Modulation of cellular mechanisms in a spinal locomotor network

    Författare :Jesper Tegnér; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neuronal Network; Calcium Channels; Calcium-DependentPotassium Channels; Neuronal Oscillator; Neuromodulation; GABAg receptors; Lamprey; Locomotion; Spinal Cord; Computer Simulation;

    Sammanfattning : Neuronal networks generate behaviour. Thus, to understand behaviour requires information on how neuronal networks work in terms of their cellular components. The overall aim of this work has been to link processes occurring at an ionic level to the operation of a neural network specialized for undulatory locomotion. LÄS MER

  5. 4. Calcium signaling in astroglial cells. Noradrenergic effects and regulation

    Författare :Håkan Muyderman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Astrocytes; Neurons; Noradrenaline; Glutamate; Fluorometry; Fura-2; Fluo-3; PBFI; Digital imaging; Voltage-patch-clamp; Whole-cell currents; Calcium; Potassium; Intercellular communication; Glutamate release; Neuron-glial interactions.;

    Sammanfattning : Astroglial cells are the most common cell type in the central nervous system and express a wide array of ion channels and neurotransmitter receptors. The cells organize into multicellular networks and exhibit a calcium-based excitability in which receptor-mediated calcium elevations propagate as intercellular waves over considerable distances. LÄS MER