Sökning: "Ca2 oscillation"

Visar resultat 6 - 6 av 6 avhandlingar innehållade orden Ca2 oscillation.

1. 6. Molecular characterization of the Ro52 autoantigen and its disease related epitopes

   Författare :Lars Ottosson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Ro52; Sjögren s syndrome; autoantibodies; congenital heart block; molecular characterization; TRIM; RBCC; Zn2 ;

   Sammanfattning : The presence of high titers of autoantibodies in patient sera is characteristic for the autoimmune disorder Sjögren s syndrome. The major targets for these autoantibodies are three intracellular proteins Ro52, Ro60 and La. It is still unclear why these proteins become targets for the immune system, and how this autoreactivity is triggered. LÄS MER