Sökning: "ortholog"
Visar resultat 1 - 5 av 44 avhandlingar innehållade ordet ortholog.
1. Structure, evolution and expression of glandular kallikrein genes
Sammanfattning : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. LÄS MER
2. Neuropeptide Y Receptors in Human, Guinea pig and Chicken : Cloning, in vitro Pharmacology and in situ Hybridization
Sammanfattning : Neuropeptide Y (NPY) is known to influence a vast number of physiological and behavioral processes such as vasoconstriction, circadian rhythms, feeding, anxiety and memory. Peptides of the NPY family bind to five different cloned G-protein coupled receptor subtypes (Y1, 2, 4-6). LÄS MER
3. Evolutionary Analysis of the Insulin-Relaxin Gene Family from the Perspective of Gene and Genome Duplication Events
Sammanfattning : Paralogs arise by duplications and belong to families. Ten paralogs (insulin; IGF-1 and -2; INSL3-6 and 3-relaxins) constitute the human insulin-relaxin family. The aim of this study was to outline the duplications that gave rise to the vertebrate insulin-relaxin genes and the chromosomal regions in which they reside. LÄS MER
4. Big data networks and orthology analysis
Sammanfattning : Understanding biological systems in complex organisms is important in life science in order to comprehend the interplay of genes, proteins, and compounds causing complex diseases. As biological systems are intricate, bioinformatics tools, models, and algorithms are of the utmost importance to understand the bigger picture and decipher biological meaning from the vast amounts of information available from biological experiments and predictions. LÄS MER
5. Cloning and characterization of neuropeptide Y receptors of the Y1 subfamily in mammals and fish
Sammanfattning : Neuropeptide Y (NPY) is an abundant neurotransmitter in the nervous system and forms a family of evolutionarily related peptides together with peptide YY (PYY), pancreatic polypeptide (PP) and polypeptide Y (PY). These peptides are ligands to a family of receptors that mediate a wide range of physiological effects including stimulation of appetite. LÄS MER