Sökning: "ortholog"

Visar resultat 1 - 5 av 42 avhandlingar innehållade ordet ortholog.

  1. 1. Structure, evolution and expression of glandular kallikrein genes

    Detta är en avhandling från Yvonne Olsson

    Författare :Yvonne Ceder; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ileum.; Clinical chemistry; Klinisk kemi; Tissue distribution; Androgen responsive element; Ortholog; Evolution; Prostate cancer; Glandular kallikreins; Prostate-specific antigen;

    Sammanfattning : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. LÄS MER

  3. 2. Neuropeptide Y Receptors in Human, Guinea pig and Chicken Cloning, in vitro Pharmacology and in situ Hybridization

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sara Holmberg; Helen Cox; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein coupled receptor; neuropeptide Y; neuropeptide Y receptor; ortholog; chicken; guinea pig; mutagenesis; receptor computer modeling; mRNA in situ hybridization; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Neuropeptide Y (NPY) is known to influence a vast number of physiological and behavioral processes such as vasoconstriction, circadian rhythms, feeding, anxiety and memory. Peptides of the NPY family bind to five different cloned G-protein coupled receptor subtypes (Y1, 2, 4-6). LÄS MER

  4. 3. Evolutionary Analysis of the Insulin-Relaxin Gene Family from the Perspective of Gene and Genome Duplication Events

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Robert Piotr Olinski; Uppsala universitet.; [2007]
    Nyckelord :Neurosciences; insulin; relaxin; insulin-like protein; gene duplication; paralogous region; Ciona intestinalis; conserved synteny; ortholog; Drosophila melanogaster; Neurovetenskap;

    Sammanfattning : Paralogs arise by duplications and belong to families. Ten paralogs (insulin; IGF-1 and -2; INSL3-6 and 3-relaxins) constitute the human insulin-relaxin family. The aim of this study was to outline the duplications that gave rise to the vertebrate insulin-relaxin genes and the chromosomal regions in which they reside. LÄS MER

  5. 4. Cloning and characterization of neuropeptide Y receptors of the Y1 subfamily in mammals and fish

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Paula Starbäck; Uppsala universitet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein; neuropeptide Y; panacreatic polypeptide; neuropeptide Y receptor; ortholog; zebrafish; guinea pig; pseudogene; evolution; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; Neurology; neurologi;

    Sammanfattning : Neuropeptide Y (NPY) is an abundant neurotransmitter in the nervous system and forms a family of evolutionarily related peptides together with peptide YY (PYY), pancreatic polypeptide (PP) and polypeptide Y (PY). These peptides are ligands to a family of receptors that mediate a wide range of physiological effects including stimulation of appetite. LÄS MER

  7. 5. Bactericidal/Permeability-Increasing Protein (BPI) and Proteinase 3: Studies at the Transcriptional Level

    Detta är en avhandling från Divison of Hematology and Transfusion Medicine, Lund University

    Författare :Katrien Pieters; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; azurophil granules; myelopoiesis; BPI; mouse ortholog; proteinase 3; transcriptional regulation; Wegener s Granulomatosis WG ; SNP; Medicine human and vertebrates ; extracellulära vätskor; Hematologi; extracellular fluids; Haematology; Medicin människa och djur ;

    Sammanfattning : In myelopoiesis, neutrophils and monocytes/macrophages are formed from a common myeloid precursor cell in the bone marow. During maturation of neutrophils, cytoplasmic granules are formed in the cells and the content of these granules is critical for the function of neutrophils in the first line of defense against invading microorganisms. LÄS MER