Sökning: "CAPILLARY ELECTROPHORESIS"

Visar resultat 11 - 15 av 132 avhandlingar innehållade orden CAPILLARY ELECTROPHORESIS.

  1. 11. Development of Capillary Electrophoresis Methods Coupled to Mass Spectrometry for Biomedical and Pharmaceutical Analysis

    Författare :Anisa Elhamili; Jonas Bergquist; Magnus Wetterhall; Douglas Westerlund; Alejandro Cifuentes; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Capillary Electrophoresis; Capillary Surface Modificaions; Electrospray Ionization; Mass Spectrometry; Peptides; Intact Proteins; Basic Pharmaceutical Drug Molecules and Complex Biological Samples; Chemistry; Kemi; Analytical Chemistry; Analytisk kemi;

    Sammanfattning : The analysis of large intact proteins and complex biological samples containing drug molecules is a common complicated task for many scientists. However, due to the importance of these molecules, there is a growing interest in pharmaceutical and medicinal research to develop rapid, highly sensitive and efficient analytical techniques. LÄS MER

  2. 12. Nanoparticle-based Capillary Electrochromatography - Separation of Small Molecules and Proteins

    Författare :Christian Nilsson; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nanoparticles; Capillary Electrochromatography; Green Fluorescent protein; Pseudostationary Phase; Capillary Electrophoresis;

    Sammanfattning : The use of nanoparticle-based pseudostationary phases (PSPs) in capillary electrochromatography (CEC) for separation of small molecules and proteins is demonstrated. A continuous full filling approach is used where the nanoparticles are suspended in the electrolyte. LÄS MER

  3. 13. Column Development in Capillary Electrophoresis and Electrochromatography for Bioanalytical Applications

    Författare :Nina Johannesson; Jonas Bergquist; Karin Markides; Abdul Malik; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Capillary electrophoresis CE ; Capillary electrochromatography CEC ; Mass spectrometry MS ; Bioanalysis; Sample pretreatment; Sol-gel; Analytisk kemi;

    Sammanfattning : Analysis of biological samples can be a difficult task. This thesis covers a broad aspect of the analytical areas of capillary electrophoresis (CE) and capillary electrochromatography (CEC) in combination with mass spectrometry (MS) that are of great importance for achieving fast, accurate and sensitive bioanalyses. LÄS MER

  4. 14. Enantiomeric separation by capillary electrophoresis : With special emphasis on the partial filling technique

    Författare :Ahmad Amini; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : Capillary electrophoresis as a powerful separation technique was employed for resolution of racemic drugs. Taurodeoxycholate (TDC), different cyclodextrins and α1- acid glycoprotein (AGP) were dissolved in the background electrolyte at low pH (3.0 to 4.0 ) as chiral selectors. LÄS MER

  5. 15. Capillary electroseparations with mass spectrometric detection Nanoparticle-based continuous full filling and applications for complex sample matrices

    Författare :Peter Viberg; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytisk kemi; Analytical chemistry; phthalates; continuous full filling; heterocyclic aromatic amines; pseudostationary phase; capillary electrophoresis; electrokinetic chromatography; capillary electrochromatography; nanoelectrospray; mass spectrometry;

    Sammanfattning : One of the major challenges in analytical chemistry is to find techniques and methods for determinations of low abundance compounds in complex sample matrices. This thesis describes the development of new miniaturised analytical techniques comprising capillary electroseparation combined with mass spectrometric detection. LÄS MER