Sökning: "Brain tumors"

Visar resultat 26 - 30 av 168 avhandlingar innehållade orden Brain tumors.

1. 26. Multimodal applications in medical technology that utilize Raman spectroscopy

   Författare :Joel Wahl; Kerstin Ramser; Mikael Sjödahl; Thomas Bocklitz; Luleå tekniska universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Raman spectroscopy; Preprocessing; Pulmonary arterial smooth muscle cells; Brain tumors; Experimental Mechanics; Experimentell mekanik;

   Sammanfattning : Biology can often be explained by structures and interactions between molecules. It is therefore of importance for medical sciences that the chemical reactions and molecular compositions of biological samples can be measured. The purpose of this thesis is twofold. LÄS MER

3. 27. Asthma and cancer among pulp and paper mill workers

   Författare :Eva Andersson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidemiology; pulp and paper industry; irritant-induced asthma; gassings; cancer; sulfate mills; sulfite mills; maintenance work; brain tumors; glioma; lung cancer; asbestos;

   Sammanfattning : There were two main aims of this thesis. One was to study if repeated high exposures to irritant gases give rise to new-onset asthma, and the other was to study if exposure in pulp and paper mills were associated with cancer. LÄS MER

4. 28. Brain tumors in children - National population-based studies on classification, diagnostics and long-term follow-up

   Författare :Elizabeth Schepke; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric CNS tumors; population-based; DNA methylation; profiling; CNS-PNET; re-evaluation; incidence rate; long-term outcome; classification; Pediatric CNS tumors; Population-based; DNA methylation; Profiling; CNS-PNET; Re-evaluation; Incidence rate; Long-term outcome; Classification;

   Sammanfattning : Although the prognosis for pediatric tumors of the central nervous system (CNS) has improved over time it is urgent to reduce mortality and improve long-term quality of life for survivors. With this aim, the first step is to identify the correct diagnosis in order to choose the right therapy and avoid unnecessary treatment. LÄS MER

5. 29. Immunological aspects of intratumoral chemotherapy and immunotherapy in malignant brain tumors

   Författare :Julio Enriquez Perez; Neurokirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma GBM ; Immunotherapy; Mouse glioma; Convection-enhanced delivery; Intratumoral chemotherapy; Glioblastom; Immuneterapi;

   Sammanfattning : Advances in surgery, chemo- and radiotherapy have only modestly improved survival rates of malignant brain tumor patients during the last decades. Emerging evidence suggests that an efficient treatment of malignant brain tumors will likely require the management of multiple aspects of tumor pathobiology in order to manipulate features as tumor heterogeneity and tumor immunosuppression. LÄS MER

7. 30. Downstream effects of master regulators in two brain diseases

   Författare :Sebastian Braun; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rett syndrome; brain tumor development; gene regulation; neural stem cells; cell of origin; BMI1;

   Sammanfattning : In paper one, we investigated how the pharmacological activation and inhibition of the glucocorticoid system affects lifespan and symptoms in a mouse model for RTT. We performed a long-term drug treatment study with the GR activator corticosterone and the GR inhibitor RU486 under which we measured the lifespan and onset of RTT-like symptoms of male Mecp2-null and female Mecp2 heterozygous mice in comparison to untreated mutant and to treated and untreated wild-type animals. LÄS MER